Results 81 to 90 of about 3,901,788 (321)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Endometriosis – especially surgical pathology?

Гинекология, 2013
The application of the combined hormonal contraceptives in the preventive maintenance of disease and the successful fight with the most common clinical manifestations of endometriosis, namely, with the syndrome EAPP (endometriosis associated pelvic pain):
A L Tikhomirov
doaj  

Role of microRNA-33a in regulating the expression of PD-1 in lung adenocarcinoma

Cancer Cell International, 2017
Background MiRNAs are vital in functioning as either oncogenes or tumor suppressors in the cell cycle. Target transcripts for immune checkpoint molecules such as PD-1/PD-L1 and (programmed cell death-1/its ligand and cytotoxic T-lymphocyte antigen 4 ...
Laura Boldrini, Mirella Giordano, Cristina Niccoli, Franca Melfi, Marco Lucchi, Alfredo Mussi, Gabriella Fontanini   +6 more
doaj   +1 more source

Validation of whole slide imaging for frozen section diagnosis in surgical pathology

Journal of Pathology Informatics, 2015
Background: Whole slide imaging (WSI) using high-resolution scanners is gaining acceptance as a platform for consultation as well as for frozen section (FS) evaluation in surgical pathology.
T. Bauer, Renee J. Slaw, J. McKenney, Deepa T. Patil   +3 more
semanticscholar   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

EFFICIENCY OF COMPLEX THERAPY OF PREMATURE WITH SURGICAL PATHOLOGY

Кубанский научный медицинский вестник, 2017
Aim. Estimate the efficiency of improved complex therapy of premature with surgical pathology.Materials and methods. 374 medical histories of premature infants were studied.
A. F. Komarov, E. I. Kleshenko, D. A. Kayumova, M. P. Yakovenko, U. B. Nekhoroshkina, M. G. Kulagina, V. I. Alekhina, E. V. Borovikova, E. P. Apalkova   +8 more
doaj   +1 more source

Accuracy of magnetic resonance imaging to identify pseudocapsule invasion in renal tumors [PDF]

, 2020
Purpose: To evaluate accuracy of MRI in detecting renal tumor pseudocapsule (PC) invasion and to propose a classification based on imaging of PC status in patients with renal cell carcinoma.
Altobelli, Emanuela, Angeletti, Silvia, Bellangino, Mariangela, Catalano, Carlo, Ciccozzi, Massimo, Del Monte, Maurizio, D’ovidio, Giulia, Faiella Eliodoro, Gallucci, Michele, Grasso, Francesco Rosario, Mastroianni, Riccardo, Muto, Giovanni, Panebianco, Valeria, Papalia, Rocco, Scarpa, Roberto Mario, Simone, Giuseppe   +15 more
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Adrenal stem cell niches are located between adrenal and renal capsules

Journal of Pediatric and Neonatal Individualized Medicine, 2016
The human adrenal glands arise around the 4th week of gestation and during the intrauterine life produce many substances that are responsible for the maintenance of fetal homeostasis and organ maturation.
Eleonora Obinu, Giorgia Locci, Clara Gerosa, Vassilios Fanos, Laura Vinci, Gavino Faa, Rossano Ambu, Cristina Loddo, Elisabetta Coni, Marco Angiolucci, Claudia Fanni, Daniela Fanni   +11 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source