Results 231 to 240 of about 2,215,729 (248)

Change in Cognition Following Ischaemic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline can occur following ischaemic stroke. How cognition changes over time and associations with cognitive change are poorly understood. This study aimed to explore these issues over 2 years following ischaemic stroke.
Wenci Yan, Terence Quinn, Alex McConnachie, Niall Broomfield, Yun Wong, David Dickie, Kirsten Forbes, Matthew Walters, Jesse Dawson   +8 more
wiley   +1 more source

Seed structure and phosphorylation in the fuzzy coat impact tau seeding competency. [PDF]

Nat Commun
Kasen A, Lövestam S, Breton L, Meyerdirk L, McPhail JA, Piche K, Louwrier A, Capan CD, Lee H, Scheres SHW, Henderson MX.   +10 more
europepmc   +1 more source

Quantity and Volume of Perivascular Spaces Are Inversely Associated With Multiple Sclerosis Relative to Cerebrovascular Disease and Migraine

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To quantify the number and volume of whole brain perivascular spaces (PVS) using a detection and segmentation algorithm in participants with multiple sclerosis (MS) and patients with disorders mimicking MS known to potentially influence PVS, such as cerebrovascular disease.
Elle M. Levit, Elizabeth A. Horwath, Daniel L. Schwartz, Lisa C. Silbert, Russell T. Shinohara, Andrew J. Solomon   +5 more
wiley   +1 more source

Correction: Cholesterol promotes autoimmune pathology through T follicular helper cells. [PDF]

Cell Mol Immunol
Li W, Tsokos GC.
europepmc   +1 more source

The Diverse Neuromuscular Spectrum of VPS13A Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective VPS13A disease (chorea‐acanthocytosis) is a rare neurodegenerative disorder caused by biallelic variants in VPS13A, typically presenting with hyperkinetic movement disorders, while neuromuscular signs are often mild. The aim of the project was to investigate the frequency and severity of neuromuscular impairment in VPS13A disease ...
Anne Buchberger, Evamaria Riedel, Marie Hackenberg, Alexander Mensch, Stefanie Beck‐Woedl, Joohyun Park, Tobias B. Haack, Bernhard Haslinger, Jan Kirschke, Holger Prokisch, Andreas Hermann, Christian Mawrin, Adrian Danek, Benedikt Schoser, Kevin Peikert, Marcus Deschauer, Isabell Cordts   +16 more
wiley   +1 more source

Pathologist-like explainable AI for interpretable Gleason grading in prostate cancer. [PDF]

Nat Commun
Mittmann G, Laiouar-Pedari S, Mehrtens HA, Haggenmüller S, Bucher TC, Chanda T, Gaisa NT, Wagner M, Klamminger GG, Rau TT, Neppl C, Compérat EM, Gocht A, Haemmerle M, Rupp NJ, Westhoff J, Krücken I, Seidl M, Schürch CM, Bauer M, Solass W, Tam YC, Weber F, Grobholz R, Augustyniak J, Kalinski T, Hörner C, Mertz KD, Döring C, Erbersdobler A, Deubler G, Bremmer F, Sommer U, Brodhun M, Griffin J, Lenon MSL, Trpkov K, Cheng L, Chen F, Levi A, Cai G, Nguyen TQ, Amin A, Cimadamore A, Shabaik A, Manucha V, Ahmad N, Messias N, Sanguedolce F, Taheri D, Baraban E, Jia L, Shah RB, Siadat F, Swarbrick N, Park K, Hassan O, Sakhaie S, Downes MR, Miyamoto H, Williamson SR, Holland-Letz T, Wies C, Schneider CV, Kather JN, Tolkach Y, Brinker TJ.   +66 more
europepmc   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source

A Multi‐Center Retrospective Cohort Study of Neurosarcoidosis Myelitis: Current Observations and Future Directions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The optimal treatment for neurosarcoidosis myelitis is uncertain. We characterize incident neurosarcoidosis myelitis and assess treatment response by MRI and clinical scales. Methods Incident probable or definite neurosarcoidosis myelitis in adults was retrospectively identified from 13 academic medical centers.
Giovanna S. Manzano, Denis Balaban, Yihan Zhang, Brian Healy, Bart K. Chwalisz, Michael Levy, Nagagopal Venna, Barney J. Stern, Carlos A. Pardo, Paula Barreras, Nicole Bou Rjeily, Eoin P. Flanagan, Vyanka Redenbaugh, Allen J. Aksamit Jr., Spencer Hutto, Max Herman, Sally El Sammak, Elsa C. Rodriguez, Laura Snider, Hannah Rains, Mayra Montalvo, Torge Rempe, Sergi Martinez Ramirez, Lucas Horta, Stacey Clardy, Jennifer Lord, Tracey A. Cho, Lama Abdel Wahed, Joseph R. Berger, Rohini D. Samudralwar, Noellie Rivera Torres, David B. Clifford, Steven Richard Dunham, Masoud Majed, Aram Zabeti, Samuel Marcucci, Yang Mao‐Draayer, Jon Doty, Paunel B. Agyei, Shamik Bhattacharyya   +39 more
wiley   +1 more source

An integrated MRI-based diagnostic framework for glioma with incomplete imaging sequences and imperfect annotations. [PDF]

NPJ Precis Oncol
Song P, Shen C, Fan Z, Yin F, Wu Y, Liu F, Zhao C, Zeng W, Xie X, Wu G, Yang B, Shi Z, Yu J.   +12 more
europepmc   +1 more source