Results 251 to 260 of about 3,537,472 (355)

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Impact of hypertension on cerebral small vessel disease: A post-mortem study of microvascular pathology from normal-appearing white matter into white matter hyperintensities. [PDF]

J Cereb Blood Flow Metab
Solé-Guardia G, Janssen A, Wolters R, Dohmen T, Küsters B, Claassen JA, Leeuw FE, Wiesmann M, Gutierrez J, Kiliaan AJ.   +9 more
europepmc   +1 more source

Researches on the pathology and diagnosis of cancers of the lung and mediastinum [PDF]

William Stokes
openalex   +1 more source

NPC1 promotes the progression of hepatocellular carcinoma by mediating the accumulation of neutrophils into the tumor microenvironment

FEBS Open Bio, Volume 15, Issue 4, Page 661-673, April 2025.
Compared to normal tissues, NPC1 expression is significantly elevated in hepatocellular carcinoma tissues. Our findings indicate that NPC1 plays a key role in regulating neutrophil recruitment within the tumor, which is a critical factor in the progression of hepatocellular carcinoma and is closely linked to poor patient outcomes.
Songhai Yang, Jiangming Chen, Kun Xie, Fubao Liu   +3 more
wiley   +1 more source

PATHOLOGY [PDF]

British Journal of Ophthalmology, 1946
openaire   +2 more sources

Making housestaff feel at home: impact of workspace interventions on anatomic pathology trainee wellness. [PDF]

Acad Pathol
Ernst K, Heisen C, Tokuyama MA, Bharani KL.   +3 more
europepmc   +1 more source

Lectures on the Pathology of Tuberculous Diseases of Bones and Joints [PDF]

, 1891
W. W. Cheyne
openalex   +1 more source

Cost‐effective and simple flow cytometry quantification of receptor‐mediated autophagy using fluorescent tagging

FEBS Open Bio, Volume 15, Issue 4, Page 587-598, April 2025.
Mitophagy, the selective degradation of damaged mitochondria, is crucial for cellular health and function. This study introduces a rapid and efficient flow cytometry method using GFP‐BNIP3L/NIX to accurately quantify mitophagy. Our approach can be adapted to use any fluorescent‐tagged selective autophagy receptor, enabling direct and rapid analysis of ...
Mija Marinković, Ana Rožić, Denis Polančec, Ivana Novak   +3 more
wiley   +1 more source

FSH enhances the inflammatory response of macrophages in the knee joint possibly through the NFκB pathway

FEBS Open Bio, Volume 15, Issue 4, Page 622-633, April 2025.
We explored the role of FSH on the synovium and found that FSH was able to mediate the development of osteoarthritis by acting on the FSH receptor (FSHR) to promote the production and release of inflammatory factors through the activation of the NFκB signaling pathway. Previous studies have suggested that women with higher follicle‐stimulating hormone (
Yu Chen, Na Xu, Wen‐wen Zhang, Yan Wang, Tong Su, Yan‐man Zhou, Jin Xu   +6 more
wiley   +1 more source

Tet2 loss and enhanced ciliogenesis suppress α-synuclein pathology. [PDF]

Acta Neuropathol Commun
Quansah E, Vatsa N, Ensink E, Brown J, Cave T, Aguileta M, Schulz E, Lindquist A, Gilliland C, Steiner JA, Escobar Galvis ML, Milčiūtė M, Henderson MX, Brundin P, Brundin L, Marshall LL, Gordevicius J.   +16 more
europepmc   +1 more source