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Important Mycoses of Wildlife: Emphasis on Etiology, Epidemiology, Diagnosis, and Pathology—A Review: PART 1

open access: yesAnimals, 2022
In the past few years, there has been a spurred tripling in the figures of fungal diseases leading to one of the most alarming rates of extinction ever reported in wild species. Some of these fungal diseases are capable of virulent infections and are now
Iniobong Chukwuebuka Ikenna Ugochukwu   +10 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Practice guideline for the histopathological diagnosis of mesothelioma (2025 version) [PDF]

open access: yesZhongguo aizheng zazhi
To improve the quality of pathologic diagnosis and enhance the standardization in pathological report of mesothelioma, Expert Committee on Pathology of Chinese Research Hospital Association and Professional Committee on Oncopathology of Shanghai ...
Expert Committee on Pathology of Chinese Research Hospital Association , Professional Committee on Tumor Pathology of Shanghai Anticancer Association
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Incidental diagnosis of bilateral synovial lipomatosis in long standing knee osteoarthritis

open access: yesHuman Pathology: Case Reports, 2015
Background: Synovial lipomatosis is a rare, benign lipoma like intra-articular lesion commonly affecting the synovial lining of knee joint causing joint pain and swelling with or without movement restriction.
Sanjushree Das, MBBS, MD Pathology   +3 more
doaj   +1 more source

Iron deficiency is not always innocent in childhood: a rare diagnosis of collagenous gastritis

open access: yesThe Turkish Journal of Pediatrics, 2022
Background. Collagenous gastritis (CG) is a very rare disease with still lots of unknowns, characterized by the subepithelial collagenous band in the gastric mucosa associated with a mixed inflammatory infiltrate in the lamina propria. Case.
Sevim Çakar, Yasemin Çakır
doaj   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

MICROSCOPIC COLITIS: CONSIDERATIONS FOR GASTROENTEROLOGISTS, ENDOSCOPISTS, AND PATHOLOGISTS

open access: yesArquivos de Gastroenterologia, 2023
Microscopic colitis is a chronic inflammatory bowel disease characterized by non-bloody diarrhea that can range from mild to severe. It is difficult to attribute up to 10-20% of chronic diarrhea to microscopic colitis.
Lorete Maria da Silva KOTZE   +3 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

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