Results 41 to 50 of about 4,561,975 (395)

A whole-slide foundation model for digital pathology from real-world data

Nature
Digital pathology poses unique computational challenges, as a standard gigapixel slide may comprise tens of thousands of image tiles1–3. Prior models have often resorted to subsampling a small portion of tiles for each slide, thus missing the important ...
Hanwen Xu, N. Usuyama, Jaspreet Bagga, Sheng Zhang, Rajesh Rao, Tristan Naumann, Cliff Wong, Zelalem Gero, Javier González, Yu Gu, Yanbo Xu, Mu-Hsin Wei, Wenhui Wang, Shuming Ma, Furu Wei, Jianwei Yang, Chun-yue Li, Jianfeng Gao, Jaylen Rosemon, Tucker Bower, Soohee Lee, R. Weerasinghe, Bill J Wright, Ari Robicsek, B. Piening, Carlo Bifulco, Sheng Wang, Hoifung Poon   +27 more
semanticscholar   +1 more source

Engaging Ideas for Pathology Student Interest Group Meetings [PDF]

, 2019
Pathology Student Interest Groups (PSIG) are a recruitment tool supported by VCU Department of Pathology to attract medical students into pathology residency.
Sanford, Kimberley
core   +1 more source

Animal models of NASH: getting both pathology and metabolic context right [PDF]

, 2015
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of referral to liver clinics, and its progressive form, non-alcoholic steatohepatitis (NASH), can lead to cirrhosis and end-stage liver disease.
Larter, Claire Z., Yeh, Matthew M.
core   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Expert consensus on precision detection of intrahepatic cholangiocarcinoma (2024 edition)

Zhongguo Linchuang Yixue
Intrahepatic cholangiocarcinoma (ICC) is a highly heterogeneous tumor, and molecular profiling serves as the foundation for personalized treatment of ICC.
Pathology Group, Chinese Society of Liver Cancer of Chinese Anti-Cancer Association; Liver Pathology Group, Chinese Society of Pathology of Chinese Anti-Cancer Association; Tumor Pathology Committee of Shanghai Anti-Cancer Association, Shanghai 200032, China
doaj   +1 more source

Avoiding chromosome pathology when replication forks collide [PDF]

, 2013
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2013 Macmillan Publishers Limited.Chromosome duplication normally initiates through the assembly of replication fork complexes at defined ...
Lloyd, RG, Nieduszynski, CA, Stockum, A, Upton, AL   +3 more
core   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives

European Respiratory Journal, 2019
Clinical and translational research has played a major role in advancing our understanding of pulmonary hypertension (PH), including pulmonary arterial hypertension and other forms of PH with severe vascular remodelling (e.g.
M. Humbert, C. Guignabert, S. Bonnet, P. Dorfmüller, J. Klinger, M. Nicolls, A. Olschewski, S. Pullamsetti, R. Schermuly, K. Stenmark, M. Rabinovitch   +10 more
semanticscholar   +1 more source

Oral pathology

British Dental Journal, 2020
Firmly established as the textbook of choice on the subject, Oral Pathology is unique in its comprehensive coverage at a level suitable for both undergraduate and postgraduate dental students and practitioners.
Naomi Ramer, Molly Cohen, Trina Sengupta, Chandni Desai, John W. Hellstein, Beomjune B. Kim, Ryan J. Smart, Waleed Zaid, Prashanth Konatham-Haribabu   +8 more
semanticscholar   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source