Results 191 to 200 of about 28,459 (282)

Career choice and interdisciplinary education in forensic pathology: a cross-sectional study. [PDF]

BMC Med Educ
Aungst J, Giffen M, Handberg E, Quinton R, Parker G, Fedor J, Bucci L, Kolatorowicz A, Menendez MJ, Gowitt G, Gill J.   +10 more
europepmc   +1 more source

Clinicopathological and molecular heterogeneity of amyloid‐β in unnatural deaths under 70 years: A forensic autopsy–based study

Brain Pathology, EarlyView.
This study investigates amyloid‐beta (Aβ) pathology in a forensic autopsy cohort of relatively young individuals (40–69 years). Using detailed immunohistochemical analyses of multiple Aβ species, we demonstrate marked regional and molecular heterogeneity, particularly within the striatum.
Shojiro Ichimata, Yukiko Hata, Koji Yoshida, Ryo Tanaka, Shigeo Murayama   +4 more
wiley   +1 more source

Fatal Self-Inflicted Chop Wound by a Supari Cutter (Sudi): A Rare Case With Forensic Analysis of Wound Patterns and Weapon Biomechanics. [PDF]

Cureus
G VK, Modi AM.
europepmc   +1 more source

EPHX2 Loss Promotes CRC Migration via EET‐Dependent Chemokine Elevation and Mitochondrial Defect

Cancer Science, EarlyView.
Loss of EPHX2 promotes EET accumulation, which in turn enhances CXCL and ROS production, thereby promoting the migratory and invasive abilities of CRC cells. ABSTRACT Epoxide hydrolase 2 (EPHX2) is a key enzyme in fatty acid metabolism that metabolizes epoxyeicosatrienoic acids (EETs), lipid mediators involved in inflammation, angiogenesis, and ...
Jianjun Zhu, Jingjia Chang, Zhiyong Li, Jin Wu, Pengfei Yu, Jingjing Zheng, Li Li, Jia Tao, Hao Wu, Yintao Li, Ming Liu   +10 more
wiley   +1 more source

Histopathological Profile of the Heart in Sudden Death: Forensic Perspectives on Cardiac and Noncardiac Mechanisms. [PDF]

Int J Appl Basic Med Res
Zorlak-Cavcic A, Camdžic N, Hodžic E, Kapo SM, Maric E, Derviševic E.   +5 more
europepmc   +1 more source

Targeting PCSK9 in Vascular Smooth Muscle Cells: An Effective Strategy to Suppress Ferroptosis and Attenuate Abdominal Aortic Aneurysm Progression

Cell Proliferation, EarlyView.
PCSK9 aggravates AAA by promoting ferroptosis in VSMCs. In the pathological AAA environment, PCSK9 upregulation triggers ferritinophagy‐dependent degradation of FTH1, leading to Fe2+ release, triggering lipid peroxidation and ferroptosis, exacerbating AAA.
Mengdie Xia, Man Li, Yanyu Chen, Jialin Chen, Yuting Cui, Xi‐Long Zheng, Jing Yang, Bingzhao Li, Xiaofeng Ma, Miao Liu, Gang Fan, Juan Peng, Xiaoyan Dai, Zhihan Tang   +13 more
wiley   +1 more source

Alzheimer neuropathological change, α-synuclein and transactive response DNA-binding protein of 43 kDa expression in children and young adult brains from forensic autopsies: Value for early measurement of abnormal protein expression prevalence in neurodegenerative diseases. [PDF]

J Neuropathol Exp Neurol
Calderón-Garcidueñas L, Nalbantoglu OU, González-Maciel A, Torres-Jardón R.   +3 more
europepmc   +1 more source

Lichenoid and Granulomatous Stomatitis: Three Additional Cases and Detailed Immunohistochemical Analysis

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Lichenoid and granulomatous stomatitis (LGS) is a rare condition, with clinicopathological features resembling lichenoid and granulomatous dermatitis. Despite increasing reports, its etiology remains unclear and detailed immunohistochemical (IHC) studies are lacking.
Mariana Paravani Palaçon, Karina Kendelhy Santos, Karina Helen Martins, Cecília Aparecida de Oliveira Campos, Ana Terezinha Marques Mesquita, Evânio Vilela Silva, Thales Peres Candido Moreira, Gabriel Enrique Tantalean Laor, Victor Hugo Toral‐Rizo, Alan Grupioni Lourenço, Heitor Albergoni Silveira, Jorge Esquiche León, Andreia Bufalino   +12 more
wiley   +1 more source

A Forensic Approach to Perioperative Deaths After Non-Cardiac Surgery: A Narrative Review. [PDF]

Diagnostics (Basel)
Tattoli L, Accogli A, Montana A, Pradelle I, De Gasperi A, Neri M.   +5 more
europepmc   +1 more source