Results 201 to 210 of about 25,030 (290)

MicroRNAs in Cardiovascular Diseases and Forensic Applications: A Systematic Review of Diagnostic and Post-Mortem Implications. [PDF]

Int J Mol Sci
Sacco MA, Gualtieri S, Verrina MC, Cordasco F, Monterossi MD, Grimaldi G, Mastrangelo H, Mazza G, Aquila I.   +8 more
europepmc   +1 more source

The DNA/RNA autophagy protein SIDT2 as a novel neuropathological hallmark in Huntington disease

Brain Pathology, EarlyView.
SIDT2‐immunoreactive inclusions are observed in the striatum, cerebral cortex, and hypothalamus in HD cases with different Vonsattel grades, and the frequency of SIDT2‐immunoreactive inclusions is associated with longer CAG repeats in the huntingtin gene.
Sanaz Gabery, Sofia Bergh, Chrisovalantou Huridou, Rachel Y. Cheong, Barbara Baldo, Paul Günther Scheunemann, Marie‐Louisa Schoebel, Linda Holmquist Mengelbier, Elisabet Englund, Catriona McLean, Carsten Saft, Deniz Kirik, Maria Björkqvist, Glenda Halliday, Elisabeth Petrasch‐Parwez, Huu Phuc Nguyen, Jonasz Jeremiasz Weber, Åsa Petersén   +17 more
wiley   +1 more source

Autopsy practices for high-consequence infectious diseases: global guidelines, alternatives, and the BSL-4 gap. [PDF]

Emerg Microbes Infect
Allgoewer K, Lavenia A, Secco L, Schaller T, Fitzek A, Kriebel C, Azeke AT, Kondo T, Tse R, Chui P, Schmiedel S, Ondruschka B.   +11 more
europepmc   +1 more source

Associations between TMEM106B C‐terminal fragment aggregation, age, and TDP‐43 or tau pathology

Brain Pathology, EarlyView.
TMEM106B C‐terminal fragment (CTF) aggregation represents an age‐associated, common, diffuse phenomenon emerging after midlife with a weak association with TDP‐43 or tau pathology. These findings suggest that TMEM106B fibrillization may define a distinct axis of protein aggregation in the aging human brain. Abstract Transmembrane protein 106B (TMEM106B)
Albert Acewicz, Sylwia Tarka, Michał Grzegorczyk, Radosław Rzepliński, Teresa Wierzba‐Bobrowicz, Tomasz Stępień   +5 more
wiley   +1 more source

Anatomical Variant or Pathological Anomaly? A Case Report of an Asymptomatic Cardiac Apical Cleft. [PDF]

Int Med Case Rep J
Posite CM, Katongole A, Mohamed MS, Omega P, Ongaria J, Ambayo R, Byaruhanga ME, Mutumba M, Usman IM.   +8 more
europepmc   +1 more source

Dual pharmacological targeting of coactivator‐associated arginine methyltransferase 1 (CARM1) and salt inducible kinase (SIK) drives ketogenesis in both hepatocytes and mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Ketone bodies are liver‐derived circulating energy metabolites that positively impact most hallmarks of ageing. Ketone bodies increase during calorie restriction and fasting, two of the more widely perceived methods to increase health span.
Tábata Bergonci, Troels Kjær Rosenbæk, Samuel J. Windross, Ulrik B. Keiding, Estéfano Pinilla, Katrine P. Stuckert, Jakob Hansen, Camilla B. Nielsen, Jemila Peter Gomes, Lucy R. Davies, Johan Palmfeldt, Volker Loeschcke, Charlotte U. Andersen, Ulf Simonsen, Thomas B. Poulsen, Mogens Johannsen   +15 more
wiley   +1 more source

When forensic psychiatry clashes with jurisdiction: nemesis and challenges of a patient suffering from glioblastoma. [PDF]

BJPsych Open
D'Imperio A, Delessert D, Ienca M, Starke G.   +3 more
europepmc   +1 more source

Development and analytical validation of a targeted short‐read next generation sequencing‐based pharmacogenetic panel for comprehensive variant detection

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Genomic profiling of patients for genetic variants that modify the effect of specific medications has many benefits, including the possibility of avoiding toxicities and ensuring an adequate effect of the medication. Our intention was to develop a comprehensive, high‐quality pharmacogenetic test panel for clinical use ...
Anna Gréen, Nils Johan Fredriksson, Michael Andresen, Jon Jonasson, Malin Lindqvist Appell, Henrik Gréen   +5 more
wiley   +1 more source

Assessment of causality and impairment following unilateral hypoglossal nerve paralysis: A case report. [PDF]

Ulus Travma Acil Cerrahi Derg
Igde EN, Ozluoglu Igde Z, Tastekin B, Akcan R, Balseven Odabasi A.   +4 more
europepmc   +1 more source

Clinical Applicability of Artificial Intelligence–Driven Implant Planning and Surgical Guide Design in the Maxillary Esthetic Zone: A Registry‐Based Cohort Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives This study evaluated the accuracy, time efficiency, and workflow consistency of artificial intelligence (AI)‐assisted versus human expert (HI) implant planning in the esthetic anterior maxilla. Material and Methods Thirty‐five single‐tooth anterior maxillary cases with paired cone beam computed tomography (CBCT) and intraoral scans (
Eslam Abdelwahab Dawood, Bahaaeldeen M. Elgarba, Rocharles Cavalcante Fontenele, Reinhilde Jacobs   +3 more
wiley   +1 more source