Results 61 to 70 of about 68,158 (337)

Postmortem submersion interval estimation of cadavers recovered from freshwater based on gut microbial community succession

Frontiers in Microbiology, 2022
Microbial community succession during decomposition has been proven to be a useful tool for postmortem interval (PMI) estimation. Numerous studies have shown that the intestinal microbial community presented chronological changes after death and was ...
Fuyuan Zhang, Pengfei Wang, Pengfei Wang, Kuo Zeng, Huiya Yuan, Huiya Yuan, Ziwei Wang, Xinjie Li, Haomiao Yuan, Shukui Du, Dawei Guan, Dawei Guan, Linlin Wang, Linlin Wang, Rui Zhao, Rui Zhao   +15 more
doaj   +1 more source

LncRNA THUMPD3‐AS1 Regulates Behavioral and Synaptic Structural Abnormalities in Schizophrenia via miR‐485‐5p and ARHGAP8

Advanced Science, EarlyView.
Schizophrenia (SCZ) is linked to synaptic structural deficits driven by dysregulated noncoding RNAs. Using the novel ceRNAxis pipeline, THUMPD3‐AS1/miR‐485‐5p/ARHGAP8 is identified as a key regulator of actin cytoskeletal remodeling through noncanonical RhoB/C‐ROCK2 signaling. Modulating this axis ameliorates SCZ‐like phenotypes in mice and aligns with
Xiaojuan Gong, Lingxi Chen, Xin Guo, Anna Jiang, Yayi He, Chunxia Yan, Liang Ma, Jiayang Gao, Jinyu Zhang, Bao Zhang   +9 more
wiley   +1 more source

PlantID – DNA-based identification of multiple medicinal plants in complex mixtures [PDF]

, 2012
Background An efficient method for the identification of medicinal plant products is now a priority as the global demand increases. This study aims to develop a DNA-based method for the identification and authentication of plant species that can be ...
Bremner, Paul, Fowler, Mark, Graham, Eleanor, Howard, Caroline, Scott, Nigel, Slater, Adrian, Socratous, Eleni, Williams, Sarah   +7 more
core   +2 more sources

Assessing the Nature of Human Brain‐Derived Extracellular Vesicles on Synaptic Activity Via the Development of an Air‐liquid Microfluidic Platform

Advanced Science, EarlyView.
This seminal study highlights the interwoven and tightly regulated functions of brain‐derived extracellular vesicles. Using microfluidics, proteomics, and AI‐based electric signal analyses of cortical brain explants, this work provides a useful resource dataset revealing the composition of human brain‐derived extracellular vesicles obtained from ...
Corentin Bernou, Yukiko Iwasaki, Willy Lutz, Glaucia Almeida, Emilie Béchard, François Delalande, Magali Rompais, Jules Bouget, Barbara Gorda, Chantal Cazevieille, Yonis Bare, Christine Carapito, Sophie Colomb, Gowrishankar Ganesh, Raphael Gaudin   +14 more
wiley   +1 more source

A student selected component (SSC) in applied forensic medicine and pathology: 'the language of trauma' [PDF]

, 2022
Richard Martin Jones
openalex   +1 more source

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

Advanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang, Binbin Zhao, Min Jia, Yan Zhao, Ye Lu, Wenyu Xi, Ziyu Zhu, Xiaojuan Gong, Qingyan Ma, Yuan Gao, Yijie Guo, Pan Li, Feng Zhu, Shuguang Wei, Xiancang Ma, Yunpeng Wang   +15 more
wiley   +1 more source

Screening of the HBx transactivation domain interacting proteins and the function of interactor Pin1 in HBV replication

Scientific Reports, 2021
Hepatitis B virus (HBV) X protein (HBx) has been determined to play a crucial role in the replication and transcription of HBV, and its biological functions mainly depend on the interaction with other host proteins.
Qiaoxia Zhou, Libo Yan, Baofu Xu, Xue’er Wang, Xuehong Sun, Ning Han, Hong Tang, Feijun Huang   +7 more
doaj   +1 more source

Variation of the intraocular pressure in relation to time of death: Contribution to the determination of the true postmortem interval (PMI) [PDF]

, 2019
Introducción: La determinación del momento del fallecimiento, es un dato de singular importancia en Medicina Legal constituyendo por su complejidad en uno de los problemas que necesita evaluación objetiva en la Patología Forense.
Genero, Sebastian, Gerometta, Rosana María del Rosario, Larroza, Gerardo Omar, Pimpinella, Pascual   +3 more
core  

NADH‐Reductive Stress Induced by Dihydrolipoamide Dehydrogenase Activation Contributes to Cuproptosis

Advanced Science, EarlyView.
This study demonstrates a cuproptosis mechanism involving nicotinamide adenine dinucleotide (NADH)‐reductive stress in neural cells. Copper activates dihydrolipoamide dehydrogenase under mitochondrial pH, accumulating NADH. Copper also induces mitochondrial permeability transition pore opening, facilitating NADH translocation to the cytosol and ...
Si‐Yi Zhang, Xing‐Hua Ren, Cheng‐Hong Zhang, Zhan‐You Wang   +3 more
wiley   +1 more source

Forensic Pathology of Society-Oriented Expert Identification Institutions in China: A Retrospective Study by 11-year Data from Academy of Forensic Science

Journal of Forensic Science and Medicine
Objective: The aim of the study was to introduce the development of forensic pathology for social-oriented forensic-identification institutions, using the Academy of Forensic Science as an example.
Yuan-Yuan Liu, En-Hao Fu, Ya-Wen Liu, Dong-Hua Zou, Jiang Huang, Hao-Jie Qin, Ning-Guo Liu   +6 more
doaj   +1 more source