Results 141 to 150 of about 1,906,254 (260)

Sustainable Entrepreneurship Emergence as Practice: A Multi-Level Pathway Model. [PDF]

F1000Res
Pardede G, Sijabat R, Parani R, Tan JD, Ataupah J, Yatmo AH, Bisowarno SD.   +6 more
europepmc   +1 more source

Towards a Parsimonious Pathway Model of Modifiable and Mediating Risk Factors Leading to Diabetes Risk. [PDF]

Int J Environ Res Public Health, 2021
Ho YL, Lee VSY, Ho MR, Lin GJ, Thumboo J.   +4 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Approach or avoidance? A dual-pathway model of job crafting in response to generative AI and its impact on career sustainability. [PDF]

Front Psychol
Liu Y, Lei H, Qu X.
europepmc   +1 more source

Applying the Dynamic Dual Pathway Model of Approach Coping to Collective Action Among Advantaged Group Allies and Disadvantaged Group Members. [PDF]

Front Psychol, 2022
Radke HRM, Kutlaca M, Becker JC.
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

3D printing of an optic pathway model from 7T MRI for education. [PDF]

3D Print Med
Black JA, Blezek DJ, Hanson CR, Crudele NA, Duit AM, Black DF, Morris JM.   +6 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Neurological Severity Versus Biomarker Dynamics in Post-Stroke Dysphagia: A Dual-Pathway Model for Functional Recovery and Feeding Transition. [PDF]

J Clin Med
Savas M, Kahraman Begen S, Onen MS, Uzun H.   +3 more
europepmc   +1 more source

On mechanisms, pathways and their models

Biology & Philosophy
Abstract Lauren Ross has recently argued that the current philosophical enthusiasm for mechanisms poses a threat to a proper understanding of the diversity of causal structures found in biology, and of the diversity of ways in which biologists explain biological phenomena.
openaire   +1 more source