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Biochemical Pathways and Modeling

Clinical Obstetrics & Gynecology, 2020
The precise etiology of the biochemical changes and the resulting constellation of symptoms seen in polycystic ovary syndrome (PCOS) has remained a mystery. Despite advances in our knowledge, the pathogenesis and alterations in the biochemical pathways underlying this disease are still not fully understood.
Anthony, Deangelis   +3 more
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Decision pathway modeling

Journal of Chemometrics, 2004
AbstractPattern recognition is playing an increasingly important role in chemical and biochemical data analysis. Many of these pattern recognition applications call for the discrimination of more than two classes of objects. Decision pathway modeling is proposed as a novel pattern recognition technique for multigroup classification.
Anthony J. Myles, Steven D. Brown
openaire   +1 more source

Modelling Computerised Clinical Pathways

1998
Since the mid 1980s, paper clinical pathways have been used in defining the road map of patient care. They have been used with varying degree of success for providing more cost-effective healthcare and helped to establish quality improvement models for healthcare delivery.
S, Chu, B, Cesnik
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Mathematical models of metabolic pathways

Current Opinion in Biotechnology, 1999
There have been recent advances in metabolic flux analysis. In particular, the marriage of traditional flux balancing with NMR isotopomer distribution analysis holds great promise for the detailed quantification of physiology. Nevertheless, flux analysis yields only static snap-shots of metabolism.
J, Varner, D, Ramkrishna
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Logic models of pathway biology

Drug Discovery Today, 2008
Living systems seamlessly perform complex information processing and control tasks using combinatorially complex sets of biochemical reactions. Drugs that therapeutically modulate the biological processes of disease are developed using single protein target strategies, often with limited knowledge of the complex underlying role of the targets ...
Watterson, S., Marshall, S., Ghazal, P.
openaire   +3 more sources

Gene Regulation Pathway Modeling

2020 9th Mediterranean Conference on Embedded Computing (MECO), 2020
Gene regulation is a process by which cells regulate the production of proteins. The purpose of this paper is to investigate how the cell will react if the four basic molecules included in the gene regulation pathway change in specific cases using MATLAB's SimBiology application.
Azra Cutuk   +3 more
openaire   +1 more source

Modeling Biochemical Pathways

2010
Sequence analysis methods predict macromolecule properties and intermolecular interactions. These data can be used to reconstruct molecular networks, which are complex systems that regulate cell functions. Systems biology uses mathematical modeling and computer-based numerical simulations in order to understand emergent properties of these systems ...
Mosca Ettore, Milanesi Luciano
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Modelling Oxidative Stress Pathways

2020
Oxidative stress occurs as a result of an imbalance in reactive oxygen species (ROS) and antioxidant defences within the cells. It plays a key role in many physiological disease states, ranging from Alzheimer’s to cancer, as well as in infectious diseases; for instance, oxidative stress is significant during bacterial infection where macrophages and ...
Harry Beaven, Ioly Kotta-Loizou
openaire   +1 more source

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