Results 41 to 50 of about 1,910,959 (261)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks +5 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille +9 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian +13 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan +1 more
wiley +1 more source
SUPPLY CHAIN MODELED AS A METABOLIC PATHWAY
Mathematical Modelling and Analysis, 2018 A new model of economic production process is proposed (in the form of a set of ODEs) based on an idea that nonconsumable factors of production facilitate the conversion of inputs to output in much the same catalytic way as do enzymes in living cells when transforming substrates into different chemical compounds.
Almaz Mustafin, Aliya Kantarbayeva
openaire +4 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi +10 more
wiley +1 more source
Disease, Models, Variants and Altered Pathways—Journeying RGD Through the Magnifying Glass
Computational and Structural Biotechnology Journal, 2016 Understanding the pathogenesis of disease is instrumental in delineating its progression mechanisms and for envisioning ways to counteract it. In the process, animal models represent invaluable tools for identifying disease-related loci and their genetic
Victoria Petri +9 more
doaj +1 more source
From databases to modelling of functional pathways [PDF]
Comparative and Functional Genomics, 2004 AbstractThis short review comments on current informatics resources and methodologies in the study of functional pathways in cell biology. It highlights recent achievements in unveiling the structural design of protein and gene networks and discusses current approaches to model and simulate the dynamics of regulatory pathways in the cell.
openaire +4 more sources
Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas
Pediatric Blood &Cancer, EarlyView.ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall +2 more
wiley +1 more source
Frontiers in Oncology, 2020 Notch suppression by gamma-secretase inhibitors is a valid approach against melanoma. However, most of studies have evaluated the short-term effect of DAPT on tumor cells or even cancer stem cells.
Faezeh Keyghobadi +11 more
doaj +1 more source