Results 51 to 60 of about 10,535,177 (317)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Mode of Action Frameworks in Toxicity Testing and Chemical Risk Assessment [PDF]

, 2009
Recently, legislative mandates worldwide are requiring systematic consideration of much larger numbers of chemicals. This necessitates more efficient and effective toxicity testing, as a basis to be more predictive in a risk assessment context.
Dep IRAS, Risk Assessment of Toxic and Immunomodulatory Agents, Meek, B.   +2 more
core   +1 more source

A study of the multi-tiered risk assessment method of site groundwater contamination considering transport-induced risk

Shuiwen dizhi gongcheng dizhi, 2023
Contaminants in groundwater can spread downstream, causing risks to receptors along the path. The risk assessment of our current site groundwater contamination focuses mainly on human health risks.
Xingzhou ZHANG, Leyi YIN, Jian CHEN, Xiaoxiao ZHOU, Lihu YANG, Jichun WU, Yueqing XIE   +6 more
doaj   +1 more source

From pathways to people: applying the adverse outcome pathway (AOP) for skin sensitization to risk assessment

ALTEX, 2013
Consumer safety risk assessment of skin sensitization requires information on both consumer exposure to the ingredient through product use and the hazardous properties of the ingredient. Significant progress has been made in determining the hazard potential of ingredients without animal testing.
Cameron, MacKay, Michael, Davies, Vicki, Summerfield, Gavin, Maxwell   +3 more
openaire   +3 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

A closer look at bioaccumulation of petroleum hydrocarbon mixtures in aquatic worms. [PDF]

, 2010
Petroleum hydrocarbons (oils) are ubiquitous in the aquatic environment, and adequate risk assessment is thus essential. Bioaccumulation plays a key role in risk assessment, but the current knowledge on bioaccumulation of oils is limited. Therefore, this
Dep IRAS, Jonker, M.T.O., Risk Assessment of Toxic and Immunomodulatory Agents, Muijs, B.   +3 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Commodity risk assessment of Acer plants from Ukraine

EFSA Journal
The European Commission requested the EFSA Panel on Plant Health to prepare and deliver risk assessments for commodities listed in Commission Implementing Regulation (EU) 2018/2019 as ’High‐risk plants, plant products and other objects'.
EFSA Panel on Plant Health (PLH), Antonio Vicent Civera, Paula Baptista, Anna Berlin, Elisavet Chatzivassiliou, Jaime Cubero, Nik Cunniffe, Eduardo de laPeña, Nicolas Desneux, Francesco Di Serio, Anna Filipiak, Beata Hasiów‐Jaroszewska, Hervé Jactel, Blanca B. Landa, Lara Maistrello, David Makowski, Panagiotis Milonas, Nikos T. Papadopoulos, Roel Potting, Hanna Susi, Dirk Jan van DerGaag, Andrea Battisti, Claude Bragard, Hugo Mas, Daniel Rigling, Massimo Faccoli, Alžběta Mikulová, Fabio Stergulc, Eugen Christoph, Olaf Mosbach‐Schulz, Franz Streissl, Paolo Gonthier   +31 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Commodity risk assessment of Lonicera ligustrina var. pileata, Lonicera ligustrina var. yunnanensis and Lonicera periclymenum plants from the UK

EFSA Journal
The European Commission requested the EFSA Panel on Plant Health to prepare and deliver risk assessments for commodities listed in Commission Implementing Regulation (EU) 2018/2019 as ‘High risk plants, plant products and other objects’.
EFSA Panel on Plant Health (PLH), Antonio Vicent Civera, Paula Baptista, Anna Berlin, Elisavet Chatzivassiliou, Jaime Cubero, Nik Cunniffe, Eduardo de laPeña, Nicolas Desneux, Francesco Di Serio, Anna Filipiak, Paolo Gonthier, Beata Hasiów‐Jaroszewska, Hervé Jactel, Blanca B. Landa, Lara Maistrello, David Makowski, Panagiotis Milonas, Nikos T. Papadopoulos, Hanna Susi, Dirk Jan van derGaag, Jane Debode, Juan A. Navas‐Cortes, Christos Kritikos, Maria Kormpi, Dimitrios Papachristos, Chrysavgi Reppa, Antigoni Akrivou, Spyridon Antonatos, Despoina Beris, Olaf Mosbach Schulz, Monia Federica Lombardo, Ciro Gardi, Roel Potting   +33 more
doaj   +1 more source