Results 71 to 80 of about 10,535,177 (317)

Uncertainties in risk assessment of dioxin-like compounds : A focus on systemic relative potencies and species differences [PDF]

open access: yes, 2014
This thesis describes experimental work undertaken to reduce uncertainties in the risk assessment of dioxin-like compounds. The toxic equivalency factor (TEF) approach is the most commonly used method for assessing the risk of complex mixtures of dioxin ...
Dep IRAS   +2 more
core  

Commodity risk assessment of Prunus cerasus × Prunus canescens hybrid plants from Ukraine

open access: yesEFSA Journal
The European Commission requested the EFSA Panel on Plant Health to prepare and deliver risk assessments for commodities listed in Commission Implementing Regulation (EU) 2018/2019 as ‘High‐risk plants, plant products and other objects’.
EFSA Panel on Plant Health (PLH)   +35 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Exposure to chemicals and metals and risk of amyotrophic lateral sclerosis: a systematic review [PDF]

open access: yes, 2009
Environmental exposure to chemicals and metals may contribute to the risk of sporadic amyotrophic lateral sclerosis (ALS). Two systematic reviews of the literature on these topics performed according to the well-established MOOSE guidelines are presented.
Veldink, J.H.   +9 more
core   +1 more source

Pest risk assessment of Spodoptera frugiperda for the European Union

open access: yesEFSA Journal, 2018
EFSA was asked for a partial risk assessment of Spodoptera frugiperda for the territory of the EU focussing on the main pathways for entry, factors affecting establishment, risk reduction options and pest management. As a polyphagous pest, five commodity
EFSA Panel on Plant Health (EFSA PLH Panel)   +27 more
doaj   +1 more source

Assessment of risk based on variant pathways and establishment of an artificial neural network model of thyroid cancer

open access: yesBMC Medical Genetics, 2019
Background This study aimed to establish an artificial neural network (ANN) model based on variant pathways to predict the risk of thyroid cancer. Methods The RNASeq data of 482 thyroid cancer samples were downloaded from the TCGA database.
Yinlong Zhao   +3 more
doaj   +1 more source

Implementing the right care in the right place at the right time for non-alcoholic fatty liver disease (NAFLD-RRR study): a study protocol for a community care pathway for people with type 2 diabetes

open access: yesBMC Health Services Research, 2022
Background Non-alcoholic fatty liver disease (NAFLD) is an emerging epidemic that affects approximately half of all people with type 2 diabetes. Those with type 2 diabetes are a high-risk NAFLD subgroup because of their increased risk of clinically ...
Lucy Gracen   +9 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

On long-term credit risk assessment and rating : Towards a new set of models [PDF]

open access: yes, 2009
Technical ReportInstitutional investors are supposed to assess credit risk by using a combination of quantitative information such as option models and qualitative assessments.
Kubo, Hideya, Sakai, Yasuhiro
core  

Particulate air pollution, coronary heart disease and individual risk assessment: a general overview. [PDF]

open access: yes, 2009
Both long-term and short-term exposure to air pollution is associated with a marked increase in cardiovascular morbidity and mortality because of the coronary syndrome and its complications.
Twickler, M.   +15 more
core   +1 more source

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