Results 81 to 90 of about 10,535,177 (317)

Commodity risk assessment of Castanea sativa plants from the United Kingdom

EFSA Journal
The European Commission requested the EFSA Panel on Plant Health to prepare and deliver risk assessments for commodities listed in Commission Implementing Regulation (EU) 2018/2019 as ‘High risk plants, plant products and other objects’.
EFSA Panel on Plant Health (PLH), Antonio Vicent Civera, Paula Baptista, Elisavet Chatzivassiliou, Jaime Cubero, Nik Cunniffe, Eduardo de laPeña, Nicolas Desneux, Anna Filipiak, Paolo Gonthier, Beata Hasiów‐Jaroszewska, Hervé Jactel, Blanca B. Landa, Lara Maistrello, David Makowski, Panagiotis Milonas, Nikos T. Papadopoulos, Roel Potting, Hanna Susi, Dirk Jan van derGaag, Pedro Gómez, Annemarie Fejer Justesen, Andrea Lucchi, Gregor Urek, Jonathan Yuen, Lucia Zappala, Umberto Bernardo, Giovanni Bubici, Anna Vittoria Carluccio, Michela Chiumenti, Francesco Di Serio, Elena Fanelli, Paraskevi Kariampa, Cristina Marzachì, Agata Kaczmarek, Louise Matic, Dora Mijic, Olaf Mosbach‐Schulz, Anna Berlin   +38 more
doaj   +1 more source

Multi-hazard risk assessment and management: pathways for the Sendai Framework and beyond [PDF]

Geoscience Communication
Abstract. Multi-hazard events pose increasingly complex challenges as natural hazards interact in cascading and compounding ways that amplify risks beyond individual hazards. Understanding these interactions – from hazard processes to cascading effects across social, economic, governance, and infrastructure systems – is critical for effective disaster ...
Tiggeloven, Timothy, Raymond, Colin, de Ruiter, Marleen C., Sillmann, Jana, Thieken, Annegret H., Buijs, Sophie L., Ciurean, Roxana, Cordier, Emma, Crummy, Julia M., Cumiskey, Lydia, De Polt, Kelley, Duncan, Melanie, Ferrario, Davide M., Jäger, Wiebke S., Koks, Elco E., van Maanen, Nicole, Murdock, Heather J., Mysiak, Jaroslav, Nirandjan, Sadhana, Poschlod, Benjamin, Priesmeier, Peter, Sairam, Nivedita, Schweizer, Pia-Johanna, Stolte, Tristian R., Zenker, Marie-Luise, Daniell, James E., Fekete, Alexander, Geiß, Christian M., van den Homberg, Marc J. C., Juhola, Sirkku K., Kuhlicke, Christian, Lebek, Karen, Šakić Trogrlić, Robert, Schneiderbauer, Stefan, Torresan, Silvia, van Westen, Cees J., Claassen, Judith N., Khazai, Bijan, Murray, Virginia, Schlumberger, Julius, Ward, Philip J.   +40 more
openaire   +7 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Degradation of a novel herbicide fluchloraminopyr in soil: Dissipation kinetics, degradation pathways, transformation products identification and ecotoxicity assessment

Environment International
With the continuous application of new agricultural chemicals in agricultural systems, it is imperative to study the environmental fate and potential transformation products (TPs) of these chemicals to better assess their ecological and health risks, as ...
Wentao Zhou, Wenbo Zhang, Huiluan Han, Xiaohu Wu, Jun Xu, Fengshou Dong, Yongquan Zheng, Xiangwei Wu, Xinglu Pan   +8 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Commodity risk assessment of Salix unrooted cuttings from the UK

EFSA Journal
The European Commission requested the EFSA Panel on Plant Health to prepare and deliver risk assessments for commodities listed in Commission Implementing Regulation (EU) 2018/2019 as ‘High risk plants, plant products and other objects’.
EFSA Panel on Plant Health (PLH), Antonio Vicent Civera, Paula Baptista, Anna Berlin, Elisavet Chatzivassiliou, Jaime Cubero, Nik Cunniffe, Eduardo de laPeña, Nicolas Desneux, Francesco Di Serio, Anna Filipiak, Beata Hasiów‐Jaroszewska, Hervé Jactel, Blanca B. Landa, Lara Maistrello, David Makowski, Panagiotis Milonas, Nikos T. Papadopoulos, Roel Potting, Hanna Susi, Dirk Jan van DerGaag, Andrea Battisti, Claude Bragard, Hugo Mas, Daniel Rigling, Massimo Faccoli, Alžběta Mikulová, Fabio Stergulc, Franz Streissl, Paolo Gonthier   +29 more
doaj   +1 more source

Adverse outcome pathways – development and potential regulatory application

Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia, 2021
Introduction: Over the last two decades, chemical safety assessment and regulatory toxicology have progressed from empirical science based on direct observation of apical adverse outcomes in whole organisms to a predictive practice that infers outcomes ...
Thania Rios Rossi Lima, Nathália Pereira de Souza, Lílian Cristina Pereira, João Lauro Viana de Camargo   +3 more
doaj  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Development and Application of Biomonitoring Equivalents for Interpreting Biomonitoring Data in a Human Health Risk Context [PDF]

, 2009
Increasingly sensitive analytical tools allow measurement of trace concentrations of chemicals in human biologic media in persons from the general population. Such data are being generated by biomonitoring programs conducted by the U.S.
Dep IRAS, Hays, S.M., Risk Assessment of Toxic and Immunomodulatory Agents   +2 more
core   +1 more source

Commodity risk assessment of Hamamelis mollis plants from the UK

EFSA Journal
The European Commission requested the EFSA Panel on Plant Health to prepare and deliver risk assessments for commodities listed in Commission Implementing Regulation (EU) 2018/2019 as ‘High risk plants, plant products and other objects’.
EFSA Panel on Plant Health (PLH), Antonio Vicent Civera, Paula Baptista, Anna Berlin, Elisavet Chatzivassiliou, Jaime Cubero, Nik Cunniffe, Eduardo de laPeña, Nicolas Desneux, Francesco Di Serio, Anna Filipiak, Paolo Gonthier, Beata Hasiów‐Jaroszewska, Hervé Jactel, Blanca B. Landa, Lara Maistrello, David Makowski, Panagiotis Milonas, Nikos T. Papadopoulos, Hanna Susi, Dirk Jan van derGaag, Jane Debode, Juan A. Navas‐Cortes, Christos Kritikos, Maria Kormpi, Dimitrios Papachristos, Chrysavgi Reppa, Antigoni Akrivou, Spyridon Antonatos, Despoina Beris, Olaf Mosbach Schulz, Monia Federica Lombardo, Ciro Gardi, Roel Potting   +33 more
doaj   +1 more source