Results 11 to 20 of about 5,776,246 (295)
KEGG for taxonomy-based analysis of pathways and genomes
Nucleic Acids Res., 2022 KEGG (https://www.kegg.jp) is a manually curated database resource integrating various biological objects categorized into systems, genomic, chemical and health information.
M. Kanehisa +4 more
semanticscholar +1 more source
Inflammation and tumor progression: signaling pathways and targeted intervention
Signal Transduction and Targeted Therapy, 2021 Cancer development and its response to therapy are regulated by inflammation, which either promotes or suppresses tumor progression, potentially displaying opposing effects on therapeutic outcomes.
Huakan Zhao +6 more
semanticscholar +1 more source
Autophagy and autophagy-related pathways in cancer
Nature reviews. Molecular cell biology, 2023 Maintenance of protein homeostasis and organelle integrity and function is critical for cellular homeostasis and cell viability. Autophagy is the principal mechanism that mediates the delivery of various cellular cargoes to lysosomes for degradation and ...
Jayanta Debnath, Noor Gammoh, K. Ryan
semanticscholar +1 more source
KEGG: new perspectives on genomes, pathways, diseases and drugs
Nucleic Acids Res., 2016 KEGG (http://www.kegg.jp/ or http://www.genome.jp/kegg/) is an encyclopedia of genes and genomes. Assigning functional meanings to genes and genomes both at the molecular and higher levels is the primary objective of the KEGG database project.
M. Kanehisa +4 more
semanticscholar +1 more source
Osteoarthritis: pathogenic signaling pathways and therapeutic targets
Signal Transduction and Targeted Therapy, 2023 Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects more than 500 million population worldwide. OA was believed to be caused by the wearing and tearing of articular cartilage, but it is now more commonly ...
Q. Yao +9 more
semanticscholar +1 more source
Targeting cancer stem cell pathways for cancer therapy
Signal Transduction and Targeted Therapy, 2020 Since cancer stem cells (CSCs) were first identified in leukemia in 1994, they have been considered promising therapeutic targets for cancer therapy. These cells have self-renewal capacity and differentiation potential and contribute to multiple tumor ...
Liqun Yang +10 more
semanticscholar +1 more source
Angiogenic signaling pathways and anti-angiogenic therapy for cancer
Signal Transduction and Targeted Therapy, 2023 Angiogenesis, the formation of new blood vessels, is a complex and dynamic process regulated by various pro- and anti-angiogenic molecules, which plays a crucial role in tumor growth, invasion, and metastasis.
Zhenling Liu +4 more
semanticscholar +1 more source
KOBAS 2.0: a web server for annotation and identification of enriched pathways and diseases
Nucleic Acids Res., 2011 High-throughput experimental technologies often identify dozens to hundreds of genes related to, or changed in, a biological or pathological process. From these genes one wants to identify biological pathways that may be involved and diseases that may be
C. Xie +9 more
semanticscholar +1 more source
BMJ Open, 2023 Introduction The early infant caregiving environment is crucial in the formation of parent–child relationships, neurobehavioural development and thus child outcomes.
Shane A Norris +8 more
doaj +1 more source
The interaction between ferroptosis and inflammatory signaling pathways
Cell Death and Disease, 2023 Ferroptosis is an iron-dependent regulated cell death driven by excessive lipid peroxidation. Inflammation is one common and effective physiological event that protects against various stimuli to maintain tissue homeostasis. However, the dysregulation of
Yue Chen +4 more
semanticscholar +1 more source