Results 11 to 20 of about 2,920,676 (267)
Metabolomics, Pathway Regulation, and Pathway Discovery [PDF]
Metabolomics is a data-based research strategy, the aims of which are to identify biomarker pictures of metabolic systems and metabolic perturbations and to formulate hypotheses to be tested. It involves the assay by mass spectrometry or NMR of many metabolites present in the biological system investigated.
Guo-Fang, Zhang +3 more
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The Pathway Tools Pathway Prediction Algorithm [PDF]
The PathoLogic component of the Pathway Tools software performs prediction of metabolic pathways in sequenced and annotated genomes. This article provides a detailed presentation of the PathoLogic algorithm. The algorithm consists of two phases. The reactome inference phase infers the reactions catalyzed by the organism from the set of enzymes present ...
Karp, Peter D. +2 more
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The Reactome Pathway Knowledgebase [PDF]
Abstract The Reactome Knowledgebase (https://reactome.org) provides molecular details of signal transduction, transport, DNA replication, metabolism and other cellular processes as an ordered network of molecular transformations in a single consistent data model, an extended version of a classic metabolic map.
Antonio Fabregat +22 more
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Stress response pathways, toxicity pathways and adverse outcome pathways [PDF]
The aim of this editorial is to address ambiguities and misconceptions regarding the terms stress response pathways, toxicity pathways and adverse outcome pathways. A large number of tightly regulated stress response pathways have evolved to allow cells to cope with and manage different types of cell stress. The purpose of these pathways is to maintain
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Pathways for Conservation [PDF]
Next week, conservation scientists will gather at the International Congress for Conservation Biology (ICCB) in Baltimore, Maryland, to grapple with the challenges of preserving our natural world in the face of a growing and increasingly consumptive human population.
Susan M, Haig +3 more
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Total Lipopolysaccharide from the Human Gut Microbiome Silences Toll-Like Receptor Signaling
Cohabitation of microbial communities with the host enables the formation of a symbiotic relationship that maintains homeostasis in the gut and beyond. One prevailing model suggests that this relationship relies on the capacity of host cells and tissues ...
Eva d’Hennezel +3 more
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Introduction The early infant caregiving environment is crucial in the formation of parent–child relationships, neurobehavioural development and thus child outcomes.
Shane A Norris +8 more
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The Covid-19 pandemic has ushered in a period of educational disruption on an unprecedented scale. During this time of crisis, education will not be business as usual, and EdTech alone cannot close the learning gap.
Katy Jordan +3 more
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Background With an extensive rise in the number of acute patients and increases in both admissions and readmissions, hospitals are at times overcrowded and under immense pressure and this may challenge patient safety.
Cathrine Bell +3 more
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Philip Alexander, MD, is a native Texan, retired physician, and accomplished musician and artist. After 41 years as an internal medicine physician, Dr. Phil retired from his practice in College Station in 2016. A lifelong musician and former music professor, he often performs as an oboe soloist for the Brazos Valley Symphony Orchestra.
Philip Alexander, Aryan Rezvani
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