Results 221 to 230 of about 7,950,605 (408)
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Molecular Oncology, EarlyView.Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp +4 morewiley +1 more sourceOncogenic Signaling Pathways in The Cancer Genome Atlas.
Cell, 2018 F. Sánchez-Vega, Marco Mina, J. Armenia, W. Chatila, Augustin Luna, Konnor C. La, Sofia G. Dimitriadoy, David L. Liu, Havish S. Kantheti, Sadegh Saghafinia, D. Chakravarty, Foysal Daian, Qingsong Gao, Matthew H. Bailey, Wen-Wei Liang, S. Foltz, I. Shmulevich, L. Ding, Zachary J. Heins, Angelica Ochoa, Benjamin E. Gross, Jianjiong Gao, Hongxin Zhang, Ritika Kundra, C. Kandoth, Istemi Bahceci, L. Dervishi, U. Dogrusoz, Wanding Zhou, Hui Shen, P. Laird, G. Way, C. Greene, Han Liang, Yonghong Xiao, Chen Wang, A. Iavarone, A. Berger, T. Bivona, A. Lazar, G. Hammer, T. Giordano, L. Kwong, G. McArthur, Chenfei Huang, A. Tward, M. Frederick, F. McCormick, M. Meyerson, E. Allen, A. Cherniack, G. Ciriello, C. Sander, N. Schultz, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, M. Kasapi, M. Ferguson, C. Hutter, H. Sofia, R. Tarnuzzer, Zhining Wang, Liming Yang, J. Zenklusen, J. Zhang, Sudha Chudamani, Jia Liu, Laxmi Lolla, R. Naresh, T. Pihl, Qiang Sun, Yunhu Wan, Ye Wu, Juok Cho, T. DeFreitas, S. Frazer, Nils Gehlenborg, G. Getz, David I Heiman, Jaegil Kim, M. Lawrence, Pei Lin, S. Meier, M. Noble, G. Saksena, Douglas Voet, Hailei Zhang, Brady Bernard, N. Chambwe, Varsha Dhankani, T. Knijnenburg, R. Kramer, Kalle Leinonen, Yuexin Liu, Michael Miller, Sheila M. Reynolds, V. Thorsson, Wei Zhang, Rehan Akbani, B. Broom, A. Hegde, Z. Ju, R. Kanchi, Anil Korkut, Jun Li, Shiyun Ling, Wenbin Liu, Yiling Lu, G. Mills, Kwok-Shing Ng, A. Rao, Michael J. Ryan, Jing Wang, J. Weinstein, Jiexin Zhang, Adam Abeshouse, I. Bruijn, Benjamin E. Gross, Zachary J. Heins, Konnor C. La, M. Ladanyi, Moriah G. Nissan, Sarah M. Phillips, E. Reznik, R. Sheridan, S. O. Sumer, Yichao Sun, B. Taylor, Jioajiao Wang, Pavana Anur, Myron Peto, P. Spellman, C. Benz, Joshua M. Stuart, Christopher K. Wong, C. Yau, D. Hayes, J. Parker, M. Wilkerson, Adrian Ally, M. Balasundaram, R. Bowlby, Denise Brooks, R. Carlsen, E. Chuah, Noreen Dhalla, Robert W. Holt, Steven J. M. Jones, K. Kasaian, Darlene Lee, Yussanne Ma, M. Marra, Michael Mayo, Richard A. Moore, A. Mungall, K. Mungall, A. G. Robertson, S. Sadeghi, J. Schein, Payal Sipahimalani, Angela Tam, N. Thiessen, Kane Tse, Tina Wong, Ashton C. Berger, R. Beroukhim, C. Cibulskis, S. Gabriel, G. Gao, G. Ha, S. Schumacher, J. Shih, M. Kucherlapati, R. Kucherlapati, Stephen Baylin, L. Cope, Ludmila V. Danilova, Moiz Bootwalla, Phillip H. Lai, D. Maglinte, D. V. Berg, D. Weisenberger, J. Auman, S. Balu, T. Bodenheimer, C. Fan, K. Hoadley, A. Hoyle, S. Jefferys, Corbin D. Jones, S. Meng, P. Mieczkowski, Lisle E. Mose, Amy H. Perou, C. Perou, J. Roach, Yan Shi, J. Simons, Tara J. Skelly, Matthew G. Soloway, Donghui Tan, Umadevi Veluvolu, Huihui Fan, T. Hinoue, Michelle Bellair, K. Chang, K. Covington, C. Creighton, H. Dinh, H. Doddapaneni, L. Donehower, J. Drummond, R. Gibbs, R. Glenn, Walker Hale, Yi Han, Jianhong Hu, V. Korchina, Sandy Lee, L. Lewis, Wei Li, Xiuping Liu, M. Morgan, Donna Morton, D. Muzny, J. Santibanez, Margi Sheth, E. Shinbrot, Linghua Wang, Min Wang, D. Wheeler, Liu Xi, Fengmei Zhao, J. Hess, Elizabeth L. Appelbaum, Matthew H. Bailey, M. Cordes, C. Fronick, L. Fulton, R. Fulton, E. Mardis, M. McLellan, Christopher A. Miller, Heather K. Schmidt, R. Wilson, D. Crain, Erin E. Curley, J. Gardner, Kevin R Lau, D. Mallery, S. Morris, J. Paulauskis, R. Penny, C. Shelton, T. Shelton, M. Sherman, E. Thompson, P. Yena, Jay Bowen, J. Gastier-Foster, M. Gerken, K. Leraas, T. Lichtenberg, N. Ramirez, L. Wise, E. Zmuda, N. Corcoran, T. Costello, C. Hovens, A. Carvalho, A. D. Carvalho, José H. Fregnani, A. Longatto-Filho, R. Reis, C. Scapulatempo-Neto, H. C. Silveira, D. O. Vidal, Andrew Burnette, J. Eschbacher, B. Hermes, Ardene Noss, Rosy Singh, Matthew L. Anderson, Patricia D. Castro, M. Ittmann, D. Huntsman, B. Kohl, X. Le, Richard A. Thorp, C. Andry, Elizabeth R. Duffy, V. Lyadov, O. Paklina, G. Setdikova, A. Shabunin, M. Tavobilov, C. McPherson, R. Warnick, R. Berkowitz, Daniel Cramer, C. Feltmate, N. Horowitz, A. Kibel, M. Muto, C. Raut, A. Malykh, J. Barnholtz-Sloan, Wendi Barrett, K. Devine, J. Fulop, Q. Ostrom, K. Shimmel, Yingli Wolinsky, A. Sloan, A. D. Rose, F. Giuliante, M. Goodman, B. Karlan, C. Hagedorn, J. Eckman, Jodi Harr, J. Myers, Kelinda Tucker, L. A. Zach, B. Deyarmin, Hai Hu, L. Kvecher, C. Larson, R. Mural, S. Somiari, A. Vícha, T. Zelinka, Joseph Bennett, M. Iacocca, B. Rabeno, P. Swanson, M. Latour, L. Lacombe, B. Têtu, A. Bergeron, Mary McGraw, S. Staugaitis, J. Chabot, H. Hibshoosh, Antonia R. Sepulveda, Tao Su, Timothy C. Wang, O. Potapova, Olga Voronina, L. Desjardins, O. Mariani, S. Roman-Roman, X. Sastre, M. Stern, F. Cheng, S. Signoretti, A. Berchuck, D. Bigner, E. Lipp, J. Marks, S. McCall, R. McLendon, A. Secord, A. Sharp, M. Behera, D. Brat, Amy Y. Chen, K. Delman, S. Force, F. Khuri, K. Magliocca, S. Maithel, J. Olson, T. Owonikoko, A. Pickens, S. Ramalingam, Dong-Myung Shin, G. Sica, Erwin G. Van Meir, Hongzhen Zhang, Wil Eijckenboom, A. Gillis, E. Korpershoek, L. Looijenga, W. Oosterhuis, H. Stoop, K. V. Kessel, E. Zwarthoff, C. Calatozzolo, L. Cuppini, S. Cuzzubbo, F. DiMeco, G. Finocchiaro, L. Mattei, A. Perin, B. Pollo, Chu Chen, J. Houck, Pawadee Lohavanichbutr, A. Hartmann, C. Stoehr, R. Stoehr, H. Taubert, S. Wach, B. Wullich, W. Kycler, D. Murawa, M. Wiznerowicz, K. Chung, W. Edenfield, Julie M Martin, E. Baudin, G. Bubley, R. Bueno, A. Rienzo, W. Richards, S. Kalkanis, T. Mikkelsen, H. Noushmehr, L. Scarpace, N. Girard, M. Aymerich, E. Campo, E. Giné, A. Guillermo, N. V. Bang, Phan Thi Hong Hanh, Bui Duc Phu, Yufang Tang, H. Colman, K. Evason, P. Dottino, J. Martignetti, H. Gabra, H. Juhl, Teniola Akeredolu, Serghei Stepa, D. Hoon, Keun-Young Ahn, K. Kang, F. Beuschlein, A. Breggia, M. Birrer, D. Bell, M. Borad, A. Bryce, Erik Castle, V. Chandan, J. Cheville, J. Copland, M. Farnell, T. Flotte, N. Giama, T. Ho, Michael J. Kendrick, J. Kocher, Karla J. Kopp, C. Moser, D. Nagorney, D. O'Brien, B. O'neill, T. Patel, G. Petersen, F. Que, M. Rivera, L. Roberts, R. Smallridge, T. Smyrk, M. Stanton, R. Thompson, M. Torbenson, J. D. Yang, Lizhi Zhang, F. Brimo, J. Ajani, Ana Maria Angulo Gonzalez, C. Behrens, J. Bondaruk, R. Broaddus, B. Czerniak, B. Esmaeli, J. Fujimoto, J. Gershenwald, C. Guo, Christopher Logothetis, F. Meric-Bernstam, C. Morán, L. Ramondetta, D. Rice, A. Sood, P. Tamboli, T. Thompson, P. Troncoso, A. Tsao, I. Wistuba, Candace D. Carter, L. Haydu, P. Hersey, V. Jakrot +499 moresemanticscholar +1 more sourceCircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma
Molecular Oncology, EarlyView.CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes Chunmei Fan, Fenghua Tan, Jie Wu, Zhaoyang Zeng, Wenjia Guo, He Huang, Wei Xiong +6 morewiley +1 more sourceClassification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
Molecular Oncology, EarlyView.The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi +13 morewiley +1 more source
