Results 231 to 240 of about 5,776,246 (295)

Immune pathways and prenatal/perinatal environmental exposures contribute to epigenetic gestational age prediction and acceleration. [PDF]

Epigenetics
Eapen AA, Loveless IM, Pan M, Liang X, Urquhart A, Straughen JK, Cassidy-Bushrow AE, Sitarik AR, Simmerman N, Thompson E, Kottyan L, Ober C, Johnson CC, Zoratti E, Levin AM.   +14 more
europepmc   +1 more source

SIRT1 regulates cigarette smoke extract‑induced alveolar macrophage polarization and inflammation by inhibiting the TRAF6/NLRP3 signaling pathway

Fang Yang, Huiping Qin, Chao-Qun Qin, Bing Huang, Feng Gao, Yi Liao, Yanping Tang, Yan-Ju Mo, Qianjie Yang, Changming Wang   +9 more
openalex   +2 more sources

Astragalus Membranaceus Treatment Protects Raw264.7 Cells from Influenza Virus by Regulating G1 Phase and the TLR3-Mediated Signaling Pathway

, 2019
Yuxi Liang, Qiu‐Yan Zhang, Linjing Zhang, Rufeng Wang, Xiaoying Xu, Xiuhua Hu   +5 more
openalex   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Transcriptomic insights into early responses of the uterovaginal junction and vagina to avian influenza virus infection in turkey breeder hens. [PDF]

Front Physiol
Kosonsiriluk S, Santativongchai P, Reed KM, Studniski MM, Wileman BW, Boukherroub KS.   +5 more
europepmc   +1 more source

Unraveling pathogenesis and potential biomarkers for autism spectrum disorder associated with HIF1A pathway based on machine learning and experiment validation

J. Jean Cui, Heli Li, Cong Hu, Feiyan Zhang, Yunjie Li, Ying Weng, Liping Yang, Y.Q. Li, M.L. Yao, Hao Li, Xiaoping Luo, Yan Hao   +11 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Role of elevation of glycolysis in tumor-associated macrophages in glioblastoma immune evasion and therapeutic implications. [PDF]

PNAS Nexus
Chen J, Zhu L, Lawson T, Proud CG, Dai L.   +4 more
europepmc   +1 more source

IL-17A deficiency alleviates cerebral ischemia-reperfusion injury via activating ERK/MAPK pathway in hippocampal CA1 region

Yanan Li, Qi Zhang, Xupeng Wang, Fang Xu, Junfang Niu, Juan Zhao, Qiujun Wang   +6 more
openalex   +1 more source