Results 51 to 60 of about 7,950,605 (408)

MAPMAN: a user-driven tool to display genomics data sets onto diagrams of metabolic pathways and other biological processes.

The Plant Journal, 2004
MAPMAN is a user-driven tool that displays large data sets onto diagrams of metabolic pathways or other processes. SCAVENGER modules assign the measured parameters to hierarchical categories (formed 'BINs', 'subBINs').
O. Thimm, O. Bläsing, Y. Gibon, Axel Nagel, S. Meyer, Peter Krüger, J. Selbig, Lukas A Müller, S. Rhee, M. Stitt   +9 more
semanticscholar   +1 more source

The Leak Pathway: A Pathway in Flux

, 2019
The epithelial cell tight junction structure is the site of the transepithelial movement of solutes and water between epithelial cells (paracellular permeability). Paracellular permeability can be divided into two distinct pathways, the Pore Pathway mediating the movement of small ions and solutes and the Leak Pathway mediating the movement of large ...
Monaco, Ashley, Ovryn, Ben, Axis, Josephine, Amsler, Kurt   +3 more
openaire   +2 more sources

The Reactome Pathway Knowledgebase [PDF]

Nucleic Acids Research, 2013
Abstract The Reactome Knowledgebase (https://reactome.org) provides molecular details of signal transduction, transport, DNA replication, metabolism and other cellular processes as an ordered network of molecular transformations in a single consistent data model, an extended version of a classic metabolic map.
Bijay Jassal, Lisa Matthews, Guilherme Viteri, Chuqiao Gong, Pascual Lorente, Antonio Fabregat, Konstantinos Sidiropoulos, Justin Cook, Marc Gillespie, Robin Haw, Fred Loney, Bruce May, Marija Milacic, Karen Rothfels, Cristoffer Sevilla, Veronica Shamovsky, Solomon Shorser, Thawfeek Varusai, Joel Weiser, Guanming Wu, Lincoln Stein, Henning Hermjakob, Peter D’Eustachio   +22 more
openaire   +6 more sources

Implementing pediatric inpatient asthma pathways. [PDF]

, 2021
ObjectivePathways are succinct, operational versions of evidence-based guidelines. Studies have demonstrated pathways improve quality of care for children hospitalized with asthma, but we have limited information on other key factors to guide hospital ...
Cabana, Michael D, Cattamanchi, Adithya, Gupta, Nisha, Jennings, Brittany, Kaiser, Sunitha V, Parikh, Kavita   +5 more
core  

Pathways of the Heart [PDF]

Circulation: Cardiovascular Genetics, 2009
Disease heterogeneity presents a formidable challenge for clinical medicine. We are unlikely to develop successful, targeted treatments unless diagnostic schemes begin to reflect the biological complexity underlying superficially similar disease phenotypes.
Frederick P. Roth, Rahul C. Deo
openaire   +3 more sources

On Model Explanations with Transferable Neural Pathways [PDF]

arXiv, 2023
Neural pathways as model explanations consist of a sparse set of neurons that provide the same level of prediction performance as the whole model. Existing methods primarily focus on accuracy and sparsity but the generated pathways may offer limited interpretability thus fall short in explaining the model behavior.
arxiv  

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Nature, 2008
Human cancer cells typically harbour multiple chromosomal aberrations, nucleotide substitutions and epigenetic modifications that drive malignant transformation.
R. McLendon, A. Friedman, D. Bigner, Erwin G. Van Meir, D. Brat, Gena M Mastrogianakis, J. Olson, T. Mikkelsen, N. Lehman, K. Aldape, W. Yung, O. Bogler, J. Weinstein, S. Vandenberg, M. Berger, M. Prados, D. Muzny, M. Morgan, S. Scherer, A. Sabo, L. Nazareth, L. Lewis, O. Hall, Yiming Zhu, Yanru Ren, Omar Alvi, Jiqiang Yao, A. Hawes, S. Jhangiani, G. Fowler, A. Lucas, C. Kovar, Andrew Cree, H. Dinh, J. Santibanez, Vandita Joshi, M. Gonzalez-Garay, Christopher A. Miller, A. Milosavljevic, L. Donehower, D. Wheeler, R. Gibbs, K. Cibulskis, C. Sougnez, T. Fennell, Scott Mahan, Jane Wilkinson, L. Ziaugra, R. Onofrio, Toby Bloom, R. Nicol, K. Ardlie, J. Baldwin, S. Gabriel, E. Lander, L. Ding, R. Fulton, M. McLellan, J. Wallis, D. Larson, Xiaoqi Shi, R. Abbott, L. Fulton, Ken Chen, D. Koboldt, M. Wendl, R. Meyer, Yuzhu Tang, Ling Lin, John R. Osborne, Brian H. Dunford-Shore, T. Miner, K. Delehaunty, C. Markovic, Gary W. Swift, W. Courtney, C. Pohl, S. Abbott, Amy E. Hawkins, Shin Leong, C. Haipek, Heather K. Schmidt, M. Wiechert, T. Vickery, S. Scott, D. Dooling, A. Chinwalla, G. Weinstock, E. Mardis, R. Wilson, G. Getz, W. Winckler, R. Verhaak, M. Lawrence, Michael J. T. O’Kelly, James Robinson, Gabriele Alexe, R. Beroukhim, S. Carter, Derek Y. Chiang, Josh Gould, Supriya Gupta, Joshua M. Korn, C. Mermel, J. Mesirov, S. Monti, Huy L. Nguyen, Melissa Parkin, Michael Reich, Nicolas Stransky, B. Weir, L. Garraway, T. Golub, M. Meyerson, L. Chin, A. Protopopov, Jianhua Zhang, I. Perna, S. Aronson, N. Sathiamoorthy, Georgi Ren, Jun Yao, W. Wiedemeyer, Hyun Soo Kim, Won Kong Sek, Yonghong Xiao, I. Kohane, J. Seidman, P. Park, R. Kucherlapati, P. Laird, L. Cope, J. Herman, D. Weisenberger, F. Pan, D. V. Berg, L. V. Neste, Mingyu Joo, Kornel E. Schuebel, S. Baylin, D. Absher, Jun Z. Li, Audrey M. Southwick, Shannon T. Brady, A. Aggarwal, Tisha Chung, G. Sherlock, J. Brooks, R. Myers, P. Spellman, E. Purdom, L. Jakkula, A. Lapuk, H. Marr, S. Dorton, Gi Choi Yoon, Ju Han, A. Ray, V. Wang, S. Durinck, M. Robinson, Nicholas J. Wang, K. Vranizan, V. Peng, E. V. Name, G. Fontenay, J. Ngai, J. Conboy, B. Parvin, H. Feiler, T. Speed, J. Gray, C. Brennan, N. Socci, A. Olshen, B. Taylor, A. Lash, N. Schultz, B. Reva, Yevgeniy Antipin, Alexey Stukalov, Benjamin E. Gross, E. Cerami, Qingqing Wei, L. Qin, V. Seshan, L. Villafania, Magali Cavatore, L. Borsu, A. Viale, W. Gerald, C. Sander, M. Ladanyi, C. Perou, D. Hayes, M. D. Topal, K. Hoadley, Yuan Qi, S. Balu, Yan Shi, Junyuan Wu, R. Penny, M. Bittner, T. Shelton, E. Lenkiewicz, S. Morris, D. Beasley, Sheri Sanders, A. Kahn, R. Sfeir, Jessica Chen, D. Nassau, Larry Feng, E. Hickey, A. Barker, D. Gerhard, J. Vockley, C. Compton, J. Vaught, P. Fielding, M. Ferguson, C. Schaefer, Jinghui Zhang, Subha Madhavan, K. Buetow, F. Collins, P. Good, M. Guyer, B. Ozenberger, Jane L. Peterson, E. Thomson   +230 more
semanticscholar   +1 more source

The Hippo Pathway [PDF]

Cold Spring Harbor Perspectives in Biology, 2012
The Hippo pathway regulates tissue growth, and inactivation of any of four key components (HPO, WTS, SAV, and MATS) results in tissue overgrowth. Cell junctions may also modulate the pathway's activity.
Iswar K. Hariharan, Kieran F. Harvey
openaire   +3 more sources

Gesture Recognition with a Skeleton-Based Keyframe Selection Module [PDF]

arXiv, 2021
We propose a bidirectional consecutively connected two-pathway network (BCCN) for efficient gesture recognition. The BCCN consists of two pathways: (i) a keyframe pathway and (ii) a temporal-attention pathway. The keyframe pathway is configured using the skeleton-based keyframe selection module. Keyframes pass through the pathway to extract the spatial
arxiv  

Notch2 Is Required for Inflammatory Cytokine-Driven Goblet Cell Metaplasia in the Lung

Cell Reports, 2015
The balance and distribution of epithelial cell types is required to maintain tissue homeostasis. A hallmark of airway diseases is epithelial remodeling, leading to increased goblet cell numbers and an overproduction of mucus.
Henry Danahay, Angelica D. Pessotti, Julie Coote, Brooke E. Montgomery, Donghui Xia, Aaron Wilson, Haidi Yang, Zhao Wang, Luke Bevan, Chris Thomas, Stephanie Petit, Anne London, Peter LeMotte, Arno Doelemeyer, Germán L. Vélez-Reyes, Paula Bernasconi, Christy J. Fryer, Matt Edwards, Paola Capodieci, Amy Chen, Marc Hild, Aron B. Jaffe   +21 more
doaj   +1 more source