Results 51 to 60 of about 2,920,676 (267)

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris, Priya B. Shetty, Olga A. Taylor, Elizabeth G. Atkinson, Melissa A. Richard, M. Monica Gramatges, Mark Zobeck, Sandi Pruitt, Amy Hughes, M. Brooke Bernhardt, Ashley Chavana, Van Huynh, Kathleen Ludwig, Laura Klesse, Kenneth Heym, Timothy Griffin, Rodrigo Erana, Juan Carlos Bernini, Han Chen, Bing Yu, Philip J. Lupo, Karen R. Rabin, Michael E. Scheurer, Austin L. Brown, The REDIAL Consortium   +24 more
wiley   +1 more source

Efficacy of F-ACP-Containing Dental Mousse in the Remineralization of White Spot Lesions after Fixed Orthodontic Therapy: A Randomized Clinical Trial

Biomedicines
Fixed appliance (FA) therapy predisposes patients to white spot lesions (WSLs). The F-ACP complex (amorphous calcium phosphate nanoparticles enriched with carbonate and fluorine and coated with citrate) has been effective for in vitro enamel ...
Massimiliano Ciribè, Erika Cirillo, Martina Mammone, Giulia Vallogini, Paola Festa, Simone Piga, Gianmaria Fabrizio Ferrazzano, Angela Galeotti   +7 more
doaj   +1 more source

Consensus Standards and Recommendations for Developmental and Cognitive Surveillance, Screening, and Evaluation in Sickle Cell Disease: Executive Summary From the National Alliance of Sickle Cell Centers Neurocognitive Workgroup

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neurodevelopmental and neurocognitive difficulties are prevalent among individuals with sickle cell disease and warrant prompt identification and support. This Special Report provides an executive summary of standards and recommendations for surveillance, screening, and evaluation for development and cognition across the lifespan developed by ...
Alyssa M. Schlenz, Donna Murdaugh, Andrew M. Heitzer, Jennifer N. Longoria, Wendy Santos‐Modesitt, Arianna Martin, Judy Cavazos, Jeff Schatz, Catherine R. Hoyt, Alison King, Eboni I. Lance, Steven Hardy, Marsha Treadwell   +12 more
wiley   +1 more source

Examining breastfeeding self-efficacy as a mediator between maternal food insecurity and breastfeeding practices in Soweto, South Africa

The South African Journal of Clinical Nutrition
Objectives: This study examined the potential mediating effect of breastfeeding self-efficacy on the relationship between maternal food insecurity and breastfeeding status.Design: A community-based, cross-sectional study was conducted.Subjects and ...
Claire Hart, Rachana Desai, Lauren Stuart, Shane A Norris, Alessandra Prioreschi   +4 more
doaj   +1 more source

Phase Angle as an Early Functional Biomarker of Cancer‐Related Fatigue in Pediatric Oncology: A Prospective Longitudinal Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric cancer remains a leading cause of morbidity and mortality worldwide, particularly in low‐and middle‐income countries. Cancer treatment may impair nutritional status, alter body composition, and exacerbate cancer‐related fatigue (CRF).
Luís Carlos Lopes‐Junior, Luiz Claudio Barreto Silva Neto, Fabiano Kenji Haraguchi, Letícia Batista de Azevedo, Marcelo Brenner Nascimento Carlini, Raphael Manhães Pessanha, Mariana Rabello Laignier, Wesley Rocha Grippa, Tania Mara Lopes Bitti Bortolini, Gláucia Zouain‐Figueiredo, Regina Aparecida Garcia de Lima, Liliana Vasquez   +11 more
wiley   +1 more source

Impact of nurse navigation and mobile app on brain tumor patients receiving oral anticancer therapy

npj Digital Medicine
Oral anticancer agents (OAAs) are commonly prescribed for patients with primary brain tumors, but adherence can be challenging due to cognitive impairment and discontinuous treatment schedules. This subgroup analysis of the randomized phase 3 CAPRI trial
Caroline Poisson, Adeline Duflot-Boukobza, Delphine Mathivon, Mohamed Khettab, Marie Ferrua, Aude Fourcade, Naïma Lezghed, Frédéric Dhermain, François Lemare, Vanessa Puglisi, May Abbas, Mario Di Palma, Florian Scotté, Etienne Minvielle, Olivier Mir, David Guyon, Sarah N. Dumont   +16 more
doaj   +1 more source

A review of adolescent nutrition in South Africa: transforming adolescent lives through nutrition initiative

The South African Journal of Clinical Nutrition, 2020
Objective: In South Africa, urbanisation is associated with substantial burdens of adolescent overweight and obesity, making teenagers vulnerable to longer-term non-communicable diseases.
Stephanie V Wrottesley, Titilola M Pedro, Caroline H Fall, Shane A Norris   +3 more
doaj   +1 more source

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

Integrated Rheumatology-Gastroenterology Clinic: An Innovative Organisation for Patients with Multiple Autoimmune Diseases

International Journal of Integrated Care
Introduction: Patients with multiple autoimmune diseases lack continuity of care due to increasing specialisation and siloed practice in healthcare. Despite improvements in quality, this organisation has led to fragmented patient pathways, as related ...
Sarah Holm Junge Jensen, Michal Frumer, Eileen Dorte Shanti Connelly, Rene Østgård, Henning Glerup, Kate Denby, Anja Leth Egsgaard, Charlotte Weiling Appel   +7 more
doaj   +1 more source

Pathways to hypertension

The Journal of Physiology, 2008
Hypertension remains a leading risk factor for morbidity and mortality from cardiovascular disease. Elevated sympathetic nerve activity contributes to the development and maintenance of hypertension, but the central mechanisms that lead to chronic increases in sympathetic nerve activity remain unresolved (Guyenet, 2006).
openaire   +3 more sources