Results 111 to 120 of about 129,637 (314)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Patients and nurses awareness of patient’s rights: A comparative study

open access: yesHealth, Spirituality and Medical Ethics, 2014
Background and Objectives : The objective of this study was to determine and compare the general levels of awareness of patient’s rights among the patients and nurses in training hospitals in Qom province. Methods: In a descriptive analytical study,
Akram Heidari   +2 more
doaj  

Relationship between' patient's rights charter' and patients' satisfaction in gynecological hospitals. [PDF]

open access: yesBMC Health Serv Res, 2016
Farzianpour F   +3 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Doctors Ask These Questions [PDF]

open access: yes, 1960
It has been suggested that the Question Box be resumed in the pages of THE LINACRE QUARTERLY. To include this feature regularly, we will need contributions from our readers. Rare is the physician who has not on occasion been confronted with a
Lynch, John J.
core   +1 more source

Patients' rights in Kashmir [PDF]

open access: yesThe Lancet, 2020
Muhammad Magdi, Yaqoob   +1 more
openaire   +2 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Iranian Nurses, Physicians and Patients\' Lived Experiences Regarding Patient’s Rights Practice

open access: yesنشریه پرستاری ایران, 2009
Background and Aim : Patients are among the most vulnerable social groups whose particular situation makes their rights more sensitive in health care system. They relegate themselves totally to the health care system and trust to the health professionals.
Soodabeh Joolaee   +2 more
doaj  

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