Results 211 to 220 of about 2,463,634 (361)

Development of a patient-reported outcome measure in adult cystic fibrosis

, 2008
Sam Salek, Lauren Corke, R.I. Ketchell
openalex   +1 more source

Can Patient-Reported Outcome Measures Identify Cancer Patients' Most Bothersome Issues? [PDF]

, 2011
Claire Snyder, Amanda L. Blackford, Neil K. Aaronson, Symone Detmar, Michael A. Carducci, Michael Brundage, Albert W. Wu   +6 more
openalex   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

PSS21 GAP ANALYSIS FOR PATIENT-REPORTED OUTCOMES MEASURES FOR ALOPECIA [PDF]

, 2011
Brooke Dennee-Sommers, N. Galipeau, Kristina Fitzgerald, Catherine Evans, Stephen D. Daniels, Simon Burgess   +5 more
openalex   +1 more source

Assessing patient reported outcome measures: A practical guide for gastroenterologists [PDF]

, 2014
Bombardier C, Devlin NJ, Deyo RA, Domino G, Drossman DA, Masachs M, Mouzas IA, Muller S, Murphy KaCD, Nightingale F, Spaccavento S, Vandenberghe A, Verissimo R   +12 more
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Literacy levels required to complete routinely used patient-reported outcome measures in rheumatology [PDF]

, 2012
Jo Adams, Judith Chapman, Sarah Bradley, Sarah Ryan   +3 more
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

Development of the EXAcerbations of Chronic Obstructive Pulmonary Disease Tool (EXACT): A Patient-Reported Outcome (PRO) Measure

, 2010
Nancy Kline Leidy, Teresa K. Wilcox, Paul Jones, Lindsey Murray, Randall Winnette, Kellee Howard, Jennifer Petrillo, John H. Powers, Sanjay Sethi   +8 more
openalex   +1 more source