Validation of the Crohn’s Life Impact Questionnaire (CLIQ), the First Patient-Reported Outcome Measure Specific to Adults with Crohn’s Disease [PDF]
, 2013 Jeanette Wilburn +4 more
openalex +1 more source
Patient-Reported Outcome Measures in NMDA Receptor Encephalitis. [PDF]
Neurol Neuroimmunol NeuroinflammHeine J +5 more
europepmc +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Repeated Measure Analysis of Dermatitis Symptoms Evolution and Patient-Reported Outcome in N06C4: A Phase 3 Randomized Trial of Mometasone Furoate in Breast Cancer Patients Receiving Radiation Therapy [PDF]
, 2013 Terence T. Sio +9 more
openalex +1 more source
Readability of Patient-reported Outcome Measures Used in Plastic Surgery. [PDF]
Plast Reconstr Surg Glob OpenZamore Z +4 more
europepmc +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Feasibility of 4 patient-reported outcome measures in a registry setting
, 2012 Aksel Paulsen +3 more
openalex +2 more sources
A retrospective analysis: the development of patient reported outcome measures for the assessment of Crohn's disease activity [PDF]
, 2014 Reena Khanna +10 more
openalex +1 more source
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source