Results 171 to 180 of about 201,393 (313)

Main factors associated with variability in the assessment of the objective response rate. A re‐analysis of the PHEREXA phase 3 clinical trial

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Local investigators (LIs) overestimate the objective response rate (ORR) in comparison to Blinded Independent Central Reviewers (BICR) in oncology. In this study, we re‐analysed data obtained in the PHEREXA trial (NCT01026142) with the following aims: i) to confirm at the single‐patient level the discrepancy observed by analysing ...
Gennaro Daniele, Tommaso Giovagnoli, Pierluigi Navarra, Cinzia Dello Russo   +3 more
wiley   +1 more source

Engineered Perception Architecture for Healthcare [PDF]

, 2018
Bain Robert, Chandler David L., Ching Francis D. K., Coombs Bertha, Fox Michael, Franz Gerald, Hahn Sue, Health TEK, Khandve Pravin, Kyrkou Artemis, MacFarquhar Larissa, Matus Morgana, Nadin Mihai, Naz Asma, Naz Asma, Tapscott Don, Thompson Ashley Clark, Wallsmart   +17 more
core   +1 more source

Through the lens of marketing authorization holders: experience in use of real‐world data and real‐world evidence in drug development and regulatory submissions in EU

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this study was to assess the general and product‐specific experiences of MAHs use of RWD/RWE in medicines development and in their regulatory submissions, and to explore organizational aspects of MAHs related to RWD/RWE. Methods An electronic survey was conducted, and information collected directly from MAHs.
Sini M. Eskola, Aleksandar Gigov, Hubertus G. M. Leufkens, Andrew Bate, Marie Louise De Bruin, Helga Gardarsdottir   +5 more
wiley   +1 more source

Prevalencia de desnutrición en pacientes con neoplasia digestiva previa cirugía Hyponutrition prevalence among patients with digestive neoplasm before surgery

Nutrición Hospitalaria, 2008
Objetivo: Analizar la prevalencia y el grado de desnutrición de los pacientes con neoplasia digestiva resecable que van a ser sometidos a intervención quirúrgica.
L. Cid Conde, T. Fernández López, P. Neira Blanco, J. Arias Delgado, J. J. Varela Correa, F. F. Gómez Lorenzo   +5 more
doaj  

Feasibility of the patient-generated subjective global assessment in long-stay nursing home residents

, 2016
Lecture based on abstract at APNEP congress 2016, Porto.
Vigário, Antónia, Ottery, Faith D., Jager, Harriët, Pinho, João Pedro, Pinto, Paula, Santoalha, Isabel   +5 more
openaire  

‘Fish in simulated water’? A Bourdieusian analysis of Chinese doctoral students' learning experiences in Southeast Asian developing countries

British Educational Research Journal, EarlyView.
Abstract International student mobility (ISM) has historically followed a pattern of movement from developing regions to developed countries. However, in recent years, there has been a noticeable increase in the number of Chinese students pursuing doctoral studies in Southeast Asian developing countries, an area that has received relatively little ...
Yueyang Zheng, Kun Dai, Alan C. K. Cheung   +2 more
wiley   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

BMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu, Chung Yin Matthew Cheung, Liling Liu, Hoi Pan Harry Cheung, Kam Yu Tam, Dai Fei Elmer Ker, Sarah H. Cartmell, Chuanbin Mao, Zhiyong Zhang, Dan Michelle Wang   +9 more
wiley   +1 more source

Can Hybrid Organisations Solve the Paradox of the Triple Bottom Line, and Does It Need Solving?

Business Strategy and the Environment, EarlyView.
ABSTRACT This study investigates how B Corp certification enables hybrid organisations to integrate competing institutional logics of market and social purpose. Through a two‐stage qualitative design combining cross‐sector interviews with B Corps and an in‐depth case study, with a total of 30 participants, we analyse how certification supports hybrid ...
Ruth Cherrington, Amanda Ayliffe, Danielle Farrow, Constantine Manolchev   +3 more
wiley   +1 more source

Operationalising Sufficiency in an Organisational Context: A Systematic Literature Review

Business Strategy and the Environment, EarlyView.
ABSTRACT Efficiency‐led sustainability is important but often fails to deliver absolute reductions in resource use, leaving organisations exposed to rebound effects. What remains underexplored is how sufficiency, the strategic limitation of consumption and resource use, is operationalised within organisational contexts.
Shahrokh Nikou, Erik‐Jan Hultink, Nancy M. P. Bocken   +2 more
wiley   +1 more source

PATIENT-GENERATED SUBJECTIVE GLOBAL ASSESSMENT (PG-SGA): A REVIEW

International Research Journal Of Pharmacy, 2018
openaire   +1 more source