Results 51 to 60 of about 68,345,786 (284)

Patient-centered medicine and patient-oriented research: improving health outcomes for individual patients [PDF]

, 2013
Background Patient-centered medicine is developing alongside the concepts of personalized medicine and tailored therapeutics. The main objective of patient-centered medicine is to improve health outcomes of individual patients in everyday clinical ...
José A Sacristán, Sacristán José A
core   +2 more sources

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Impact of a Health Research Training Program on Patient and Community Partners, and Researchers: A Qualitative Evaluation

Health Expectations
Background Building capacity through training and education is recommended to support meaningful engagement of patient partners in health research. The Patient and Community Engagement Research (PaCER) programme is a 12‐month initiative that enables ...
Sadia Ahmed, Ingrid Nielssen, Iqmat Iyiola, Paul Fairie, Sandra Munro, Maria J. Santana   +5 more
doaj   +1 more source

Development of a minimum data set for long COVID: a Delphi study protocol

BMJ Open
Introduction Previous consensus-based long COVID research has focused on establishing research priorities, developing clinical definitions, core outcomes and a list of recommendations of patient-reported outcome measures that can be used to assess and ...
Lisa Lix, Pawan Kumar, Simon Décary, Kiran Pohar Manhas, Andrea Gruneir, Gary Groot, Alison Hoens, Gayle Halas, Angela Cheung, Kieran Quinn, Michelle Kho, Adelaide Amah, Hammed Ejalonibu, Bansari Chavda, Alaa Aburub, Renee Greene, Daphne Kemp, Donna Ellen Frederick, Kathrina Mazurik, Sarah Slagerman, Donna Ioana Dumitrescu, Anne Bhereur, Caren Cao, Grace Lam, Candace McNaughton, Kadia Saint-Onge, Diana Sanchez-Ramirez   +26 more
doaj   +1 more source

Neurocognitive, School‐Based, and Quality of Life Outcomes for Youth With Sickle Cell Disease and Thalassemia: A Scoping Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling, Hakim Tokhi, Alexander A. Boucher   +2 more
wiley   +1 more source

Patient and researcher experiences of patient engagement in primary care health care research: A participatory qualitative study

Health Expectations, 2022
Background Studies have highlighted common challenges and barriers to patient engagement in research, but most were based on patient partners' or academic researchers' experiences. A better understanding of how both groups differentially experience their
Sophie Béland, Mireille Lambert, Alannah Delahunty‐Pike, Dana Howse, Charlotte Schwarz, Maud‐Christine Chouinard, Kris Aubrey‐Bassler, Fred Burge, Shelley Doucet, Alya Danish, Olivier Dumont‐Samson, Mathieu Bisson, Alison Luke, Marilyn Macdonald, André Gaudreau, Judy Porter, Donna Rubenstein, Véronique Sabourin, Cathy Scott, Mike Warren, Linda Wilhelm, Catherine Hudon   +21 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Living With Diabetes in Alberta: Patient and Caregiver Priorities for Diabetes Care, Management, and Treatment

Health Expectations
Introduction Patients and caregivers living with diabetes experience multiple barriers to diabetes management. These include financial, geographic, and lack of culturally relevant diabetes education. Our aim was to understand the perspectives of patients
Sadia Ahmed, Paul Fairie, Iqmat Iyiola, Dorothy Nelson, Maria J. Santana   +4 more
doaj   +1 more source

“Better Than Any Medicine:” Understanding How Therapy Dogs Support Patients Presenting with Mental Health and Substance Use Concerns in an Emergency Department Setting

Patient Experience Journal
In Canada, emergency departments have a large number of patients with mental health and substance use concerns passing through their doors. Our research aim was to assess the impact that therapy dog visits may have for patients presenting with mental ...
Alexandria R. Pavelich, Colleen A. Dell, James Stempien, Holly McKenzie, Aimee Hozack, Jane Smith, Alexis Rowsell, Janet Gunderson, Elizabeth Pease   +8 more
doaj   +1 more source