Results 111 to 120 of about 2,060,078 (325)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

[Patient reported outcome measures in geriatric care: first experiences].

Tijdschrift voor gerontologie en geriatrie, 2017
01 december ...
Hems, M., Harkes, M., Moret-Hartman, M., Melis, R.J.F., Schoon, Y.   +4 more
openaire   +4 more sources

Patient-driven research priorities for patient-centered measurement

BMC Health Services Research
Background Patient-centred measurement (PCM) emphasizes a holistic approach wherein the voices of patients are reflected in the standardized use of patient-reported outcome and experience measures and are represented throughout the continuum of ...
A. Fuchsia Howard, Linda Warner, Lena Cuthbertson, Richard Sawatzky   +3 more
doaj   +1 more source

Healthcare provider characteristics that influence the implementation of individual-level patient-centered outcome measure (PROM) and patient-reported experience measure (PREM) data across practice settings: a protocol for a mixed methods systematic review with a narrative synthesis

Systematic Reviews, 2021
Background Substantial literature has highlighted the importance of patient-reported outcome and experience measures (PROMs and PREMs, respectively) to collect clinically relevant information to better understand and address what matters to patients. The
Angela C. Wolff, Andrea Dresselhuis, Samar Hejazi, Duncan Dixon, Deborah Gibson, A. Fuchsia Howard, Sarah Liva, Barbara Astle, Sheryl Reimer-Kirkham, Vanessa K. Noonan, Lisa Edwards   +10 more
doaj   +1 more source

Can virtual nature improve patient experiences and memories of dental treatment? A study protocol for a randomized controlled trial [PDF]

, 2014
Background Dental anxiety and anxiety-related avoidance of dental care create significant problems for patients and the dental profession. Distraction interventions are used in daily medical practice to help patients cope with unpleasant procedures ...
Andrade, J, Auvray, M, Bruce, M, Gabe, R, May, J, Mills, I, Moles, DR, Pahl, S, Stone, RJ, Tanja-Dijkstra, K, White, MP   +10 more
core   +4 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Patient experience and challenges in group concept mapping for clinical research. [PDF]

, 2019
BACKGROUND AND OBJECTIVE: Group concept mapping (GCM) is a research method that engages stakeholders in generating, structuring and representing ideas around a specific topic or question.
Cunningham, Amy, Doty, Amanda M.B., Gentsch, Alexzandra T., LaNoue, Marianna, Mills, Geoffrey D., Nord, Garrison, Rising, Kristin L.   +6 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Mit PROM und PREM zu Patient Centered Care

Monitor Versorgungsforschung
In Deutschland ist der aktuelle Stand der Nutzung von Patient-Reported Outcome Measures (PROM) und Patient-Reported Experience Measures (PREM) ausbaufähig. Derzeit erfolgt hierzulande die Anwendung dieser Instrumente eher noch in einem fragmentierten und
Peter Stegmaier
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source