Results 161 to 170 of about 2,863,004 (297)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Principles of Good Practice for the Translation and Cultural Adaptation Process for Patient-Reported Outcomes (PRO) Measures: Report of the ISPOR Task Force for Translation and Cultural Adaptation

, 2005
D Wild, Alyson Grove, Mona Martin, Sonya Eremenco, Sandra McElroy, A. Verjee-Lorenz, Pennifer Erikson   +6 more
openalex   +1 more source

Factors Affecting Patient Reported Outcomes after Surgical Fixation for a Lisfranc Injury

, 2022
Ashish S. Shah, Sean M. Young, Zachary Littlefield, Srihari R. Prahad, Kevin S. Luque-Sanchez, Logan Reed, Matthew R. Young   +6 more
openalex   +1 more source

Real time patient‐reported outcome measures in patients with cancer: Early experience within an integrated health system [PDF]

, 2023
Samantha Tam, Theresa Zatirka, Christine Neslund‐Dudas, Wan‐Ting Su, Cara E. Cannella, Jeewanjot S. Grewal, Ahmad Mattour, Amy Tang, Benjamin Movsas, Steven S. Chang   +9 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

The use of patient reported outcome measures (PROMs) in clinical assessment. [PDF]

, 2018
Black, Bradbury-Jones, Burton, Dawson, Drozd, Equality Act, Flynn, Goldbart, Harris, Haywood, Jette, Jones, Kavanagh, Kyte, MacArthur, Mansell, Murray, Nelson, RCN, Streiner, Wylde   +20 more
core   +1 more source

Six Sessions of Anterior-to-Posterior Ankle Joint Mobilizations Improve Patient-Reported Outcomes in Patients With Chronic Ankle Instability: A Critically Appraised Topic [PDF]

, 2018
Erik A. Wikstrom, Sajad Bagherian, Nicole B. Cordero, Kyeongtak Song   +3 more
openalex   +1 more source

Machine Learning-Based Predictive Models for 90-Day Readmission of Total Joint Arthroplasty Using Comprehensive Electronic Health Records and Patient-Reported Outcome Measures [PDF]

, 2023
Jaeyoung Park, Xiang Zhong, Emilie N. Miley, Rachel S. Rutledge, Jaquelyn Kakalecik, Matthew Johnson, Chancellor F. Gray   +6 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Telehealth in Palliative Care: A Systematic Review of Patient Reported Outcomes

, 2017
A systematic review was conducted to explore published quantitative and qualitative research describing patient-reported outcomes of palliative telehealth intervention studies.
Head, Barbara A., Schapmire, Tara J., Zheng, Yongqiang   +2 more
core