Results 171 to 180 of about 1,921,692 (262)

The Usefulness of Machine Learning Models to Predict Patient-Reported Outcome Measures in Chronic Rhinosinusitis With Nasal Polyps. [PDF]

World J Otorhinolaryngol Head Neck Surg
Shen Y, Xiong PH, Zheng BW, Li CX, Chen JL, Gu Y, Yang YH, Lu T, Yang YC.   +8 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

A severity-anchored, patient-reported outcome framework for clinical trials in post-stroke dysphagia. [PDF]

Front Neurol
Qureshi AI, Kaur G, Carhuapoma L, Lakhani P, Lefton-Greif MA, Mehr DR, Royse LA, Wang NY, Zahoor K, Hanley DF.   +9 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Patient-Reported Outcomes, Patient-Reported Information

The Patient: Patient-Centered Outcomes Research
Baldwin, Mike, Spong, Andrew, Doward, Lynda, Gnanasakthy, Ari   +3 more
openaire   +1 more source

Multilevel factors associated with nonresponse to patient-reported outcome measures in routine radiation oncology care. [PDF]

Qual Life Res
Liu JB, Chen YJ, Edelen MO, Pusic AL, Martin NE, Zeng C.   +5 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Patient Reported Outcome [PDF]

, 2020
openaire   +1 more source