Results 201 to 210 of about 2,675,009 (295)

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

Voices that matter: The impact of patient-reported outcome measures on clinical decision-making. [PDF]

World J Methodol
Jeyaraman N, Jeyaraman M, Ramasubramanian S, Balaji S, Muthu S.   +4 more
europepmc   +1 more source

Longitudinal deteriorations in patient reported outcomes in patients with COPD [PDF]

, 2006
Toru Oga, Koichi Nishimura, Mitsuhiro Tsukino, Susumu Satô, Takashi Hajiro, Michiaki Mishima   +5 more
openalex   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

The Translation and Cultural Adaptation of Patient-Reported Outcome Measures

, 2005
Stephen P. McKenna, Lynda Doward
openalex   +1 more source

The impact of the Calman–Hine report on the processes and outcomes of care for Yorkshire's colorectal cancer patients [PDF]

, 2006
Eva Morris, Raymond Haward, Mark S. Gilthorpe, Cheryl Craigs, D Forman   +4 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Meaningful differences in patient-reported outcome measurement scores in liver disease. [PDF]

Hepatol Commun
Desai AP, Orman ES, Aridi TG, Stump T, Nephew L, Ghabril MS, Fallon M, Chalasani N, Monahan P.   +8 more
europepmc   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Correction to: Estimation of the Harvey Bradshaw Index from the Patient Reported Outcome-2 in Crohn's Disease. [PDF]

Inflamm Bowel Dis
europepmc   +1 more source