Results 271 to 280 of about 7,676,849 (387)

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Development and validation of an eating behavior patient-reported outcome measure in people living with obesity or overweight. [PDF]

Obesity (Silver Spring)
Bushnell DM, Fung S, Brod M, Roberts CA, Le Roux CW, Steen O, Lucas KJ, Hennige AM, Uster A.   +8 more
europepmc   +1 more source

PAR7 ASSESSMENT OF PATIENT-REPORTED OUTCOMES AMONG OSTEOARTHRITIC PATIENTS

, 2004
SR Gandra, LW Lawrence
openalex   +1 more source

Guidance for industry: patient-reported outcome measures: use in medical product development to support labeling claims: draft guidance [PDF]

, 2006

openalex   +1 more source

Patient‐reported outcomes (PROs) versus patient‐reported outcome measures (PROMs)—Is there a difference? [PDF]

Clinical and Experimental Dental Research, 2018
openaire   +3 more sources

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Comparison of Patient-Reported Outcome Instruments in the Preoperative Evaluation of Cubital Tunnel Syndrome. [PDF]

J Hand Surg Glob Online
Carroll TJ, Chirokikh A, Jones CMC, Speach D, Ketonis C.   +4 more
europepmc   +1 more source

Longitudinal deteriorations in patient reported outcomes in patients with COPD [PDF]

, 2006
Toru Oga, Koichi Nishimura, Mitsuhiro Tsukino, Susumu Satô, Takashi Hajiro, Michiaki Mishima   +5 more
openalex   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Association of Patient-Reported Outcome Patterns and Major Clinical Factors with Frailty in Stable COPD. [PDF]

Int J Chron Obstruct Pulmon Dis
Yang M, Wang Z, Zhao Y, He J, Lin D, Wang Y, Liu Y.   +6 more
europepmc   +1 more source