Results 81 to 90 of about 7,676,849 (387)

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Outcomes of Physicians' Communication Goals During Patient Interactions. [PDF]

, 2021
During healthcare visits, physicians may set communication goals such as providing their patient with information about treatment; however, no recommendations exist regarding which goals physicians should prioritize during their often-brief interactions ...
Andrews, Sara E, Howell, Jennifer L, Hua, Jacqueline, Sweeny, Kate   +3 more
core  

Collecting patient‐reported outcome measures [PDF]

Internal Medicine Journal, 2017
AbstractPatient‐reported outcome measures (PROM) are potentially useful outcome measures that may be reported at the individual clinical, health service and/or health system level. PROM require clearly defined patient populations to enable comparisons, and are most meaningful when integrated with clinical data sets.
Susannah Ahern, Rasa Ruseckaite, Ilana N. Ackerman   +2 more
openaire   +4 more sources

Machine learning to predict individual patient-reported outcomes at 2-year follow-up for women undergoing cancer-related mastectomy and breast reconstruction (INSPiRED-001)

Breast, 2021
Background: Women undergoing cancer-related mastectomy and reconstruction are facing multiple treatment choices where post-surgical satisfaction with breasts is a key outcome.
André Pfob, Babak J. Mehrara, Jonas A. Nelson, Edwin G. Wilkins, Andrea L. Pusic, Chris Sidey-Gibbons   +5 more
doaj  

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Oncoplastic conservative surgery for breast cancer: long-term outcomes of our first ten years experience [PDF]

, 2018
The main goal of oncoplastic breast surgery (OBS) is to optimize cosmetic outcomes and reduce patient morbidity, while still providing an oncologically-safe surgical outcome and extending the target population of conservative surgery.
Barellini, L, Calabrese, C, Casella, D, Di Taranto, G, Fausto, A, Kothari, A, Lo Torto, F, Marcasciano, M, Perra, Agostino, Ribuffo, D, Sordi, S, Tarallo, M   +11 more
core   +1 more source

Extending the Range of Measurement for Minimally Invasive Treatments by Adding New Concepts to FACE-Q Aesthetics Scales

Plastic and Reconstructive Surgery, Global Open
Background:. The Satisfaction with Face Overall and Psychological Function scales are the most frequently used FACE-Q Aesthetics module scales. This study aimed to extend their range of measurement by adding and testing new concepts.
Anne F. Klassen, DPhil, Andrea L. Pusic, MD, Manraj Kaur, PhD, Charlene Rae, PhD, Lotte Poulsen, MD, PhD, Jasmine Mansouri, BSc, Elena Tsangaris, PhD, Steven Dayan, MD, Jennifer Klok, MD, Kathleen Armstrong, MD, Katherine Santosa, MD, Stefan Cano, PhD, CPsychol, AFBPsS   +11 more
doaj   +1 more source

Patient-Reported Outcome Measures in Atopic Dermatitis and Chronic Hand Eczema in Adults

Patient, 2019
Patient-reported outcome measures (PROMs) provide an important complement to physician-assessed clinical outcome measures in dermatologic diseases such as atopic dermatitis (AD) and chronic hand eczema (CHE).
A. Barrett, Julie Hahn-Pedersen, N. Kragh, E. Evans, A. Gnanasakthy   +4 more
semanticscholar   +1 more source