Results 131 to 140 of about 759,784 (262)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Reduction of pruritus and depression using longitudinal patient-reported outcome measures in hemodialysis: a quality improvement project. [PDF]

J Patient Rep Outcomes
Naar L, Mussnig S, Niknam J, Brosch F, Krenn S, Mayer CC, Beige J, Hecking M.   +7 more
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Sex-Based Differences in Patient-Reported Outcome Measures Are Not Present Three Months After ACL Reconstruction. [PDF]

J Clin Med
Alfayyadh A, Williams JR, Neal K, Khandha A, Snyder-Mackler L, Buchanan TS.   +5 more
europepmc   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Identifying Existing Guidelines, Frameworks, Checklists, and Recommendations for Implementing Patient-Reported Outcome Measures: Protocol for a Scoping Review

Randi Jayasinghe, Susannah Ahern, Ashika Maharaj, Lorena Romero, Rasa Ruseckaite   +4 more
openalex   +1 more source

The role of general practitioner empathy on patient-reported outcomes in telephone consultations: a cross-sectional study with validation of the Consultation and Relational Empathy (CARE) Measure for measuring empathy in telephone consultations [PDF]

Kieran Sweeney, Lauren Ng, Brian Kelly, Diana Stamatopoulos, Jeremy Howick, Stewart W Mercer   +5 more
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Research tools and protocols: readability of pediatric and adult patient-reported outcome measures in eosinophilic esophagitis. [PDF]

Dis Esophagus
Desai S, Green EW, Cotton CC, Dellon ES.
europepmc   +1 more source

Editor's Spotlight/Take 5: Readability of Orthopaedic Patient-reported Outcome Measures: Is There a Fundamental Failure to Communicate? [PDF]

, 2017
Montri D. Wongworawat
openalex   +1 more source