Results 111 to 120 of about 10,452,164 (251)

Patient Reported Outcome Measures: Challenges in the Reporting!

Annals of Surgery Open, 2021
Melissa N. Orr, BS, Alison K. Klika, MS, Nicolas S. Piuzzi, MD   +2 more
doaj   +1 more source

Development and validation of clinical implementation methods for patient-reported outcomes in Japanese multi-center palliative care units

Journal of Patient-Reported Outcomes
Background Patient-Reported Outcomes (PROs) are recommended for use in clinical oncology. However, they are not routinely used in professional palliative care practices in Japan.
Nao Ito, Azusa Sato, Kana Takeuchi, Tomoko Shigeno, Hiroko Sasaki, Maho Aoyama, Mitsunori Miyashita   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Developing a set of patient‐centered outcomes for routine use in endometriosis: An international Delphi study

Acta Obstetricia et Gynecologica Scandinavica
Introduction There is large variation in individual patient care for endometriosis. A uniform approach to measure outcomes could be incorporated into routine clinical practice to personalize and monitor treatments and potentially improve the quality of ...
Alba Nicolas‐Boluda, Enora Le Roux, Arounie Tavenet, Jerome Bouaziz, Paolo Vercellini, Pamela Stratton, Arnaud Fauconnier   +6 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Standardising the collection of patient-reported experience measures to facilitate benchmarking and drive service improvement [PDF]

, 2018
Patient experience teams in NHS Wales’ Health Boards and Trusts are working across the country to collect patient experience feedback from members of the public who access health care services.
Carolan-Rees, Grace, Puntoni, Sarah, Kathleen Withers, Robert Palmer, Susan O'Connell, O\u27Connell, Susan, Grace Carolan-Rees, Palmer, Robert I, Sarah Puntoni, Robert I Palmer, Kathleen L Withers, Withers, Kathleen L   +11 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Optimal functional outcome measures for assessing treatment for Dupuytren's disease: A systematic review and recommendations for future practice [PDF]

, 2013
This article is available through the Brunel Open Access Publishing Fund. Copyright © 2013 Ball et al.; licensee BioMed Central Ltd.Background: Dupuytren's disease of the hand is a common condition affecting the palmar fascia, resulting in progressive ...
Pratt, AL, Nanchahal, J, Jagdeep Nanchahal, Ball, C, Anna L Pratt, Catherine Ball   +5 more
core   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Routine use of patient-reported experience and outcome measures for children and young people: a scoping review

Systematic Reviews
Background Patient-reported outcome measures (PROMs) measure people’s views of their health status whereas patient-reported experience measures (PREMs) are questionnaires measuring perceptions of their experience whilst receiving healthcare.
Anne Alarilla, Katharine Terrell, Paula Kelly, Heather Chesters, Faith Gibson, Geralyn Oldham, Debbie Sell, Gwyneth Davies, Jo Wray   +8 more
doaj   +1 more source