Results 211 to 220 of about 817,135 (264)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Systematic review of patient-reported outcome measures for opioid use disorder recovery. [PDF]

open access: yesAddiction
Pytell JD   +9 more
europepmc   +1 more source

Patient-reported outcome measures in patients with systemic lupus erythematosus with or without concurrent fibromyalgia. [PDF]

open access: yesLupus
Gold HT   +11 more
europepmc   +1 more source

Patient-reported outcome measures in depression

Nordic Journal of Psychiatry, 2022
Patient-reported outcome measures (PROMs) are increasingly important as a mean for quality assurance. Feasible estimates of recovery can be achieved through the application of Jacobson plots, which is a simple demonstration of the outcome of each case, recommended for clinical use.
Dávid Húsdal á Steig   +4 more
openaire   +3 more sources

Choosing a patient-reported outcome measure

Theoretical Medicine and Bioethics, 2010
There has been much philosophical interest regarding the 'hierarchy of evidence' used to determine which study designs are of most value for reporting on questions of effectiveness, prognosis, and so on. There has been much less philosophical interest in the choice of outcome measures with which the results of, say, an RCT or a cohort study are ...
Leah M, McClimans, John, Browne
openaire   +2 more sources

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