Results 221 to 230 of about 1,334,045 (336)

Effect of timed exercise interventions on patient-reported outcome measures: A systematic review. [PDF]

open access: yesPLoS One
Karavetian M   +17 more
europepmc   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

open access: yesMolecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li   +12 more
wiley   +1 more source

A new generation of patient-reported outcome measures with large language models. [PDF]

open access: yesJ Patient Rep Outcomes
Terheyden JH   +4 more
europepmc   +1 more source

Repeated Measure Analysis of Dermatitis Symptoms Evolution and Patient-Reported Outcome in N06C4: A Phase 3 Randomized Trial of Mometasone Furoate in Breast Cancer Patients Receiving Radiation Therapy [PDF]

open access: bronze, 2013
Terence T. Sio   +9 more
openalex   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

Feasibility of 4 patient-reported outcome measures in a registry setting

open access: gold, 2012
Aksel Paulsen   +3 more
openalex   +2 more sources

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

open access: yesMolecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza   +3 more
wiley   +1 more source

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