Results 61 to 70 of about 1,778,197 (355)

Usage of glaucoma-specific patient-reported outcome measures (PROMs) in the Singapore context: a qualitative scoping exercise

BMC Ophthalmology, 2018
Background Despite the increasing emphasis on the role of glaucoma-specific patient-reported outcome measures (PROMs) as relevant outcome measures for the impact of glaucoma and its intervention on patients' daily lives, the feasibility of implementing ...
Owen Kim Hee, Zheng-Xian Thng, Hong-Yuan Zhu, Ecosse Luc Lamoureux   +3 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Adoption of electronic patient-reported outcomes in cancer clinical practice: the point of view of Italian patients

ESMO Real World Data and Digital Oncology
Background: In 2022, the European Society for Medical Oncology (ESMO) guideline recommended the adoption of electronic patient-reported outcomes measures (ePROMs) in routine clinical practice for patients with cancer.
A.A. Valsecchi, V. Battista, S. Terzolo, R. Dionisio, G. Lacidogna, D. Marino, V. Quarà, E. Sperti, V. Tuninetti, F. Vignani, C. Zichi, V.E. Bounous, G. Valabrega, A. Ferrero, N. Biglia, M. Di Maio   +15 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Patient‐Reported Outcomes in Venous Thromboembolism: A Systematic Review of the Literature, Current Challenges, and Ways Forward

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Venous thromboembolism (VTE) affects >1.2 million Americans annually. Although the clinical outcomes and economic burdens of VTE have been well described, the impact of VTE on patients' health status has yet to be summarized.
Daniel J. Snyder, Robert S. Zilinyi, David J. Cohen, Sahil A. Parikh, Sanjum S. Sethi   +4 more
doaj   +1 more source

The facilitators and barriers to implementing patient reported outcome measures in organisations delivering health related services: a systematic review of reviews

Journal of Patient-Reported Outcomes, 2018
BackgroundThere is increasing interest in using Patient Reported Outcome Measures (PROMs) within organisations delivering health related services. However, organisations have had mixed success in implementing PROMs and there is little understanding about
Alexis Foster, L. Croot, J. Brazier, Janet Harris, A. O’Cathain   +4 more
semanticscholar   +1 more source

Patient-reported outcome measures in cardiovascular disease [PDF]

European Heart Journal - Quality of Care and Clinical Outcomes, 2021
AbstractIn today's medical ecosystem, it is vital to measure the outcomes that are most important to the patients. As such, patient-reported outcome measures (PROMS) can be an essential metric to deliver high-quality cardiovascular care, particularly in the subset of patients who remain disappointed with their outcomes.PROMS should be a reproducible ...
openaire   +3 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Patient-Reported Outcome Measures in Cataract Surgery

TNOA Journal of Ophthalmic Science and Research
Purpose: To assess the patient-reported outcome measures and health-related quality of life in cataract patients after their cataract surgery. Method: A prospective observational pilot study was conducted on 197 patients with cataract who underwent ...
Vinitha Dharmalingam, Nirmal Fredrick, Sunitha Nirmal, Niranjan Karthik Senthil Kumar   +3 more
doaj   +1 more source

Patient-Reported Outcome Measures as Complementary Information to Clinician-Reported Outcome Measures in Patients With Psoriasis.

JAMA dermatology, 2021
Patient-Reported Outcome Measures as Complementary Information to Clinician-Reported Outcome Measures in Patients With Psoriasis Psoriasis has been associated with major changes in patients’ psychosocial, emotional, and physical functioning.
J. Barbieri, J. Gelfand
semanticscholar   +1 more source