Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Impact of efalizumab on patient-reported outcomes in high-need psoriasis patients: results of the international, randomized, placebo-controlled Phase III Clinical Experience Acquired with Raptiva (CLEAR) trial [NCT00256139] [PDF]
Jean‐Paul Ortonne+3 more
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Impact of Radiotherapy on Complications and Patient-Reported Outcomes After Breast Reconstruction
R. Jagsi+7 more
semanticscholar +1 more source
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
Reconceptualizing Patient-reported Outcomes Measures in the Australian Breast Device Registry. [PDF]
Herbert D+5 more
europepmc +1 more source
Two-Year Clinical Outcomes After Enhanced External Counterpulsation (EECP) Therapy in Patients With Refractory Angina Pectoris and Left Ventricular Dysfunction (Report from the International EECP Patient Registry) [PDF]
Özlem Soran+3 more
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Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?
Chen‐xi Li, Zhong‐cheng Gong
wiley +1 more source
The Effect of the Design of Polyethylene Inserts in Total Knee Arthroplasty on Patient Reported Outcomes. [PDF]
Gunda B+6 more
europepmc +1 more source
Metaanalysis of the correlation between radiographic tumor response and patient‐reported outcomes [PDF]
David Victorson, M. Soni, David Cella
openalex +1 more source