Results 271 to 280 of about 6,836,441 (345)

Comprehensive Conservative Care for Kidney Failure - the Need for Evidence-Based Guidance

Kidney International Reports
Olalekan Lee Aiyegbusi
doaj   +1 more source

Exploring patient-reported outcomes and morbidity burden of patients with VEXAS syndrome: a scoping review. [PDF]

EClinicalMedicine
Efficace F, Krepper D, Sparano F, Fazi P, Voso MT, Gurnari C.   +5 more
europepmc   +1 more source

SensRORing cholesterol to drive protumoral myelopoiesis

Molecular Oncology, EarlyView.
Bleve et al. uncover a cholesterol‐driven immune evasion pathway, where RORγ‐dependent myelopoiesis shapes tumor immunosuppression. Targeting RORγ and PCSK9 emerges as a strategy to boost cancer immunotherapy. Protumoral myelopoiesis is a determinant of immunoevasion and tumor spread in many malignancies.
Sara Gennari, Luigi Nezi, Teresa Manzo
wiley   +1 more source

24-month patient-reported outcomes for a novel lumbar total joint replacement. [PDF]

N Am Spine Soc J
Sivaganesan A, Koscielski M, Kabani AS, Sielatycki JA, Goldstein J, Riesgraf B, Humphreys C, Hodges S.   +7 more
europepmc   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

Correlation of patient reported outcomes among patients with chronic low back pain and controls. [PDF]

BMC Musculoskelet Disord
Baker SA, Clark KA, Gibbons AK, Gallart A, Bowden AE, Mitchell UH, Fullwood DT.   +6 more
europepmc   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Patient-Reported Outcomes During Neoadjuvant Therapy for Gastrointestinal Cancer and Their Association with Postoperative Complications. [PDF]

J Gastrointest Cancer
Shannon AH, Ruff SM, Palettas M, Sarna A, Huang E, Kneuertz PJ, Dillhoff M, Ejaz A, Pawlik TM, Cloyd JM.   +9 more
europepmc   +1 more source

Patient-reported outcomes: The next step?

Indian Journal of Urology, 2016
openaire   +4 more sources

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source