Results 281 to 290 of about 7,712,957 (388)
The Translation and Cultural Adaptation of Patient-Reported Outcome Measures
Stephen P. McKenna, Lynda Doward
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Effect of patient characteristics on reported outcomes after total knee replacement [PDF]
Antonio Escobar+6 more
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Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
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The impact of the Calman–Hine report on the processes and outcomes of care for Yorkshire's colorectal cancer patients [PDF]
Eva Morris+4 more
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Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
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Patient-reported outcome measures in emergency and acute care: looking beyond the emergency room [PDF]
Jason B. Liu, David W. Bates
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Comprehensive cancer centre (CCCs) and CCCs of Excellence (CCCoE) integration in healthcare. Through outreach to surrounding community hospitals, CCCs enable wider access to top‐clinical cancer treatments and care, thereby facilitating the swift enrolment of patients into data‐rich clinical trials (PI‐initiated trials testing new concepts, drug ...
Anton Berns+4 more
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Clinical and Patient-Reported Outcomes of Robotic Versus Laparoscopic Inguinal Hernia Repair. [PDF]
Wadhawan R+4 more
europepmc +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
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