Results 61 to 70 of about 2,966,345 (343)

Patient-Reported Outcome (PRO) Consortium translation process: consensus development of updated best practices

Journal of Patient-Reported Outcomes, 2018
This paper describes the rationale and goals of the Patient-Reported Outcome (PRO) Consortium’s instrument translation process. The PRO Consortium has developed a number of novel PRO measures which are in the process of qualification by the U.S. Food and
Sonya Eremenco, Sheryl Pease, Sarah Mann, Pamela Berry, on behalf of the PRO Consortium’s Process Subcommittee   +4 more
doaj   +1 more source

Paving the way for patient centricity in real-world evidence (RWE): Qualitative interviews to identify considerations for wider implementation of patient-reported outcomes in RWE generation

Heliyon, 2023
Objectives: Real-world evidence (RWE) generation can be enhanced by including patient-reported outcomes (PROs). Methods for collecting and using PRO data in the real-world setting are currently underdeveloped and there is no international guidance ...
Konrad Maruszczyk, Christel McMullan, Olalekan Lee Aiyegbusi, Thomas Keeley, Roger Wilson, Philip Collis, Catherine Bottomley, Melanie J. Calvert   +7 more
doaj   +1 more source

Collecting patient‐reported outcome measures [PDF]

Internal Medicine Journal, 2017
AbstractPatient‐reported outcome measures (PROM) are potentially useful outcome measures that may be reported at the individual clinical, health service and/or health system level. PROM require clearly defined patient populations to enable comparisons, and are most meaningful when integrated with clinical data sets.
Susannah Ahern, Rasa Ruseckaite, Ilana N. Ackerman   +2 more
openaire   +4 more sources

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

PEPFAR Public Health Evaluation - Care and Support - Phase 2 Kenya [PDF]

, 2009
Phase 2 consisted of a longitudinal cohort study to measure patient-reported outcomes of care and support, a costing survey, and qualitative interviews to understand patient and carer ...
Eve Namisangoi, Faith Mwangi-Powell, Grace Munene, Irene J. Higginson, Julia Downing, Mackuline Atieno, Nancy Gikaara, Richard A. Powell, Richard Harding, Scott Moreland, Suzanne Penfold, Victoria Simms, Zipporah Ali   +12 more
core  

Towards standard setting for patient-reported outcomes in the NHS homeopathic hospitals [PDF]

, 2008
We report findings from a pilot data collection study within a programme of quality assurance, improvement and development across all five homeopathic hospitals in the UK National Health Service (NHS).<p></p> <b>Aims</b> (1) To
Chanda, Clover, Concato, David H.K. Ratsey, David Reilly, Delamothe, Elizabeth A. Thompson, Elizabeth S. Baitson, Fisher, Helmut Roniger, Hugh J. Nielsen, Martien Brands, Peter Fisher, Reilly, Richardson, Robert T. Mathie, Robert W. Leckridge, Saul R. Berkovitz, Sharples, Shaw, Shaw, Spence, Stewart W. Mercer, Susan J. Barron, Thomas E. Whitmarsh, Thompson, Tom M. Kirby, Wahl, Walach, White   +29 more
core   +1 more source

Mixed methods study of views and experience of non-hospitalised individuals with long COVID of using pacing interventions

Scientific Reports
Long COVID is highly prevalent and debilitating, with key symptoms including fatigue, breathlessness, and brain fog. Pacing is an approach to energy conservation used to help people with chronic conditions like ME/CFS manage the impact of their condition,
Christel McMullan, Shamil Haroon, Grace Turner, Olalekan Lee Aiyegbusi, Sarah E. Hughes, Sarah Flanagan, Anuradhaa Subramanian, Krish Nirantharakumar, Elin Haf Davies, Chris Frost, Louise Jackson, Naijie Guan, Yvonne Alder, Amy Chong, Lewis Buckland, Felicity Jeyes, David Stanton, Melanie Calvert   +17 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Patient-Reported Outcomes in Cardiothoracic Surgery [PDF]

The Annals of Thoracic Surgery, 2019
Current studies in cardiothoracic clinical research frequently fail to use end points that are most meaningful to patients, including measures associated with quality of life. Patient-reported outcomes (PROs) represent an underused but important component of high-quality patient-centered care.
Subramanian, Melanie, Kozower, Benjamin D, Brown, Lisa M, Khullar, Onkar V, Fernandez, Felix G   +4 more
openaire   +5 more sources