Results 161 to 170 of about 51,447 (275)

Venetoclax combined with cladribine, idarubicin, cytarabine (CLIA‐VEN) results in higher remission rates over conventional 7 + 3 chemotherapy without increased toxicity in newly diagnosed acute myeloid leukaemia

open access: yesBritish Journal of Haematology, EarlyView.
Summary Induction chemotherapy in fit de novo acute myeloid leukaemia (AML) patients has historically combined an anthracycline with standard‐dose cytarabine (‘7 + 3’) despite complete response (CR) rates of 50%–70%. In May 2023, our institution adopted the utilization of cladribine, cytarabine, idarubicin and venetoclax (CLIA‐VEN) for intensive ...
Benjamin J. Lee   +11 more
wiley   +1 more source

The cost‐effectiveness of intraoperative margin assessment strategies during radical prostatectomy

open access: yesBJU International, EarlyView.
Objective To determine whether current intraoperative margin assessment (IOMA) techniques (such as Neurovascular Structure Adjacent Frozen‐section Examination [NeuroSAFE] or confocal laser microscopy [CLM]) used during radical prostatectomy (RP) to enhance nerve‐sparing surgery (NSS) while reducing positive surgical margins (PSMs) justify their extra ...
Joost van Drumpt   +7 more
wiley   +1 more source

Upstream Interventions to Promote Oral Health and Reduce Oral Health Inequalities: A Scoping Review

open access: yesCommunity Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objectives This scoping review aimed to map global evidence on upstream interventions which promote oral health and reduce socioeconomic inequalities in oral health. Methods A review was undertaken in accordance with the Joanna Briggs Institute (JBI) methodology for scoping reviews and the Preferred Reporting Items for Systematic Reviews and ...
Michelle Stennett   +6 more
wiley   +1 more source

Reframing Justice in Healthcare AI: An Ubuntu‐Based Approach for Africa

open access: yesDeveloping World Bioethics, EarlyView.
ABSTRACT There is an ongoing debate on how to balance the benefits and risks of artificial intelligence (AI), especially in healthcare. In resource‐constrained settings, such as Africa, where access to quality care remains a challenge, AI has the potential to improve efficiency, accessibility, and patient outcomes.
Aloysius Ochasi   +3 more
wiley   +1 more source

Impact of screening programmes for type 1 diabetes in youth: A systematic review and meta‐analysis

open access: yesDiabetic Medicine, EarlyView.
Abstract Aim To evaluate the impact of anti‐islet antibody (IAb) screening on the general population and first‐degree relatives (FDRs)/high‐risk individuals and evidence‐based follow‐up modalities. Methods We performed this review through systematic searches of PubMed, EMBASE, Cochrane Library, Web of Science, ClinicalTrials.gov and International ...
Roberto Franceschi   +24 more
wiley   +1 more source

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