Results 81 to 90 of about 18,422 (295)
British Journal of Clinical Pharmacology, EarlyView.Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić +4 more
wiley +1 more source
The Egyptian Journal of Radiology and Nuclear Medicine, 2018 Outline: To address the correspondence of measured and predicted doses for different malignant tumours utilizing various gamma criteria and QA for confirmation of VMAT with an EPID and 2D array detector.
Ismail E. Mohamed +4 more
doaj +1 more source
On the evaluation of patient specific IMRT QA using EPID, dynalog files and patient anatomy
, 2014 Purpose: This research, investigates the viability of using the Electronic portal imaging device (EPID) coupled with the treatment planning system (TPS), to calculate the doses delivered and verify agreement with the treatment plan.
Defoor, Dewayne Lee; Department of Radiation Oncology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA. Cancer Therapy and Research Center, San Antonio, TX, USA. +5 more
core +1 more source
Physics and Imaging in Radiation OncologyIntroduction: To evaluate the feasibility of Monte Carlo (MC)-based patient-specific quality assurance (PSQA) for MR-guided online adaptive radiotherapy and to explore the potential to eliminate the post-delivery measurement-based PSQA.
Ruiqi Li +6 more
doaj +1 more source
How the HTAR will contribute to a value‐based decision‐making for medicinal products across the EU
British Journal of Clinical Pharmacology, EarlyView.The European Union Health Technology Regulation 2021/2282 (HTAR) introduces joint assessment of health technologies (including medicinal products and medical devices) across EU Member States. It was signed into law in 2021 and came into full force in January 2025.
Roisin Adams, Michal Stanak
wiley +1 more source
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
British Journal of Clinical Pharmacology, EarlyView.CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
Patient-specific QA for moving target irradiation with a scanned ion beam in NIRS-HIMAC
, 2015 Purpose: Three-dimensional (3D) pencil-beam scanning technique has been utilized since 2011 at the Heavy Ion Medical Accelerator in Chiba (HIMAC). Beam delivery system and treatment planning software (TPS) require dosimetric patient-specific QA to check ...
原 洋介, 原, 洋介, 705095, 705094
core
, 2023 Purpose: Irregular surfaces in bolus electron conformal therapy (BECT) create target volume dose inhomogeneity, which off-axis intensity modulation (IM) can reduce.
Crist, James T
core
Exploring new avenues: Psychedelic‐assisted therapy for young people
British Journal of Clinical Pharmacology, EarlyView.Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou +3 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Background Female sex hormones used in feminizing hormone therapy (FHT) may influence activation and persistence of HIV pre‐exposure prophylaxis (PrEP) medications. The clinical relevance of this interaction remains unclear, particularly for transgender and cisgender women (TGW and CGW).
Elizabeth Hastie +10 more
wiley +1 more source