Results 141 to 150 of about 7,892,678 (288)

Virtual Nurse Discharge: Improving Patient and Nurse Experience

This case study reviews the virtual discharge nurse (VDN) process and its impact on patient experience and nursing workflow as an exemplar of an effective telehealth innovation at a community hospital 23-bed Short Stay Unit (SSU).
Wright, Fay, Oates, Carolyn, Davis, Stacey, Flihan, Dina, Odell, Christine   +4 more
core   +1 more source

Intravascular Iodinated Contrast Media Administration in Adults: A Patient Safety Approach

, 2017
In 2013, The ICPS Contrast Media Usage and Exposure Workgroup was formed to review, define, assess and implement best practices regarding the use of intravascular iodinated contrast media (CM) in diagnostic and interventional procedures with respect to ...
Indianapolis Coalition for Patient Safety
core   +1 more source

Lung Health and Respiratory Syncytial Virus: Podcast of a Patient–Physician Discussion Based on Insights from a Patient Advisory Board Meeting

Infectious Diseases and Therapy
An advisory board meeting was held with five participants living with chronic respiratory conditions or having experienced a severe episode of respiratory syncytial virus (RSV) infection, to understand the challenges faced by such individuals and their ...
Bela Vatsa, Lisa McNeil, Peter Deussen, Steven Homewood, Steven Worsnip, Frithjof Kosfeld   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Holding GLP-1 Agonists Prior to Elective Procedures

Patient Safety, 2023
Patient Safety Authority
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Enhancing System-Level Quality Improvement through Patient-Inclusive Teamwork: A Review

Engaging patients in quality improvement (QI) initiatives offers significant advantages, including increased patient satisfaction, improved outcomes, and the integration of creative insights from patient perspectives.
Mohiuddin, Shaik
core   +1 more source

Masthead - Highlights of 2023

Patient Safety, 2023
Patient Safety Authority
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source