Results 241 to 250 of about 11,275,620 (315)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Impact of culture dimensionality and matrix composition on morphology, phenotype and drug response in pancreatic cancer models. [PDF]

Sci Rep
Doelvers F, Wansch K, Kuehn A, Dragomir MP, Janik T, Joosten M, Hilfenhaus G, Vecchione L, Felsenstein M, Ma D, Lerchbaumer M, Jürgensen C, Bahra M, Duwe G, Stintzing S, Keilholz U, Pelzer U, Neumann CCM.   +17 more
europepmc   +1 more source

Case report: Onychopapilloma in a patient with BAP1 tumor predisposition syndrome-a useful clinical marker? [PDF]

Fam Cancer
Sjøstrøm E, Ahlborn LB, Eliesen EV, Wadt K, Lei U, Byrjalsen A.   +5 more
europepmc   +1 more source

From Anatomy to Innovation: Embedding Patient-Centered Design in Medical Education.

JMIR Med Educ
Koizia LJ, Vandekerckhove P, Howard S, Maisch B, Harris BHL.   +4 more
europepmc   +1 more source

Remarkable response of metaplastic breast cancer to a novel targeted AKT inhibitor TAS-117 in a Cowden syndrome patient: a case report. [PDF]

BJC Rep
Godina E, Fernández Carcaño M, Uzunparmak B, Pepper T, Shah P, Rodon J.   +5 more
europepmc   +1 more source