Results 101 to 110 of about 5,399,581 (311)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Association Between Clinicians’ Average Patient Length of Stay and Patient Experience Scores [PDF]

Objective: Given the current emphasis on patient-centered care, emergency physicians are seeking ways to improve patients’ experience in the emergency department (ED).
Pafford, Carl, Roumpf, Steven K, Vaizer, Julia, Kuhn, Diane, Pollard, Katherine, Lardaro, Thomas, Hunter, Benton R, Glober, Nancy K, Strachan, Christian C   +8 more
core   +1 more source

Is patient-centredness in European hospitals related to existing quality improvement strategies? Analysis of a cross-sectional survey (MARQuIS study). [PDF]

, 2009
BACKGROUND: There is growing recognition of patients' contributions to setting objectives for their own care, improving health outcomes and evaluating care.
Lombarts, MJMH, Klazinga, N., Groene, O., Groene, O, Thompson, A, Lombarts, M.J.M.H., Lombarts, M. J. M. H., Klazinga, N, Suñol, R, Suñol, R., Groene, Oliver, Suñol Sala, Rosa, Alonso, J., Alonso, J, Thompson, A.   +14 more
core   +2 more sources

Management of Patients With Active Caries

Journal of the California Dental Association, 2014
This paper reports on a mechanism to manage caries as a disease and to medically intervene in the disease process to halt progression. The goal of this paper is to provide this alternative to a surgical-only approach. The management of caries begins with assessing lesion activity and the potential for arrest.
openaire   +2 more sources

Angina in patients with an active lifestyle [PDF]

European Heart Journal, 1996
The care of the active angina patient comprises risk stratification, risk factor modification, cardiac rehabilitation and pharmacotherapy. Risk stratification may be undertaken using a symptom limited exercise test, with the possibility of myocardial perfusion imaging to improve sensitivity. Higher risk patients may be evaluated angiographically.
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Creating and sustaining a culture of accountability for patient experience [PDF]

, 2014
Improving the quality of the patient experience has become an imperative for healthcare organizations. Value-based payment models include patient perception data, and a negative experience can impact an organization’s finances.
Didehban, Roshanak, MHS, FACHE, Fasolino, John P., MD, Kennedy, Denise M., MBA   +2 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Editorial: Aging-related factors in digital health: Design, uptake, engagement, and outcomes

Frontiers in Digital Health, 2023
OraLee H. Branch, Sarah A. Graham, Raeanne C. Moore, Patricia A. Areán   +3 more
doaj   +1 more source

A TRANSITION FROM DISEASE-CENTRED TO GOAL-DIRECTED INDIVIDUALISED CARE OF PATIENTS WITH MULTIPLE MORBIDITIES: A JOURNEY TO GOAL-ORIENTATED PATIENT HEALTHCARE

European Medical Journal Innovations, 2018
Goal-orientated healthcare is multi-level strategic planning of medical care in which the patient’s goals are set first and, thereafter, their operationalisation is implemented into clinical practice.
Katarzyna Rygiel
doaj