Results 131 to 140 of about 349,440 (263)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Patient and public involvement in pragmatic trials: online survey of corresponding authors of published trials [PDF]

, 2023
Shelley Vanderhout, Pascale Nevins, Stuart G. Nicholls, Colin Macarthur, Jamie Brehaut, Beth K. Potter, Katie Gillies, Beatriz Goulão, Maureen Smith, Alicia Hilderley, Kelly Carroll, Anne Spinewine, Charles Weijer, Dean Fergusson, Monica Taljaard   +14 more
openalex   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

An international cross-sectional study of dementia researchers' own perspectives on patient and public involvement. [PDF]

Sci Rep
Fusdahl P, Hernandez DC, Baldera JP, Rongve A, Khachaturian A, Aarsland D, Testad I, Borda MG.   +7 more
europepmc   +1 more source

Realising the potential of patient and public involvement to make a difference: what can trial teams do? [PDF]

, 2015
Bridget Young, Louise Dudley, Paula Williamson, Carrol Gamble   +3 more
openalex   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source

Patient and Public Involvement and Engagement within a UK blood cancer cohort: a case study. [PDF]

Res Involv Engagem
Howell D, Miller C, Rebane A, Sheridan R, Roman E, Smith A.   +5 more
europepmc   +1 more source

Positive reporting? Is there a bias is reporting of patient and public involvement and engagement? [PDF]

, 2016
Carolyn Chew‐Graham
openalex   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Public and patients involvement in chronic illness care, a way to provide universal health coverage in poor resource setting - a case study

, 2018
S. Kumaran, Rajendra Surenthirakumaran, A.Q.M. Nurul Haq, A. Nithiyalingam, R. Gobith   +4 more
openalex   +2 more sources