Results 121 to 130 of about 383,023 (311)

Patient and public involvement toolkit for antimicrobial medicines development research [PDF]

, 2018
PPI is a rapidly growing and important global movement. PPI specifically in antimicrobial medicines development research, however, is new and unfamiliar.
Kok, Michele, Grier, Sally, Evans, David, MacGowan, Alasdair, Gibson, Andy   +4 more
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Co‐Creation of a Study Protocol to Assess the Effect of Transcranial Direct Current Stimulation in the Management of Fatigue in Children and Young People With Acquired Brain Injury (Fatiguebrain‐tDCS)

Health Expectations
Background Children and young people (CYP) with moderate/severe acquired brain injury (ABI) often have problems with chronic cognitive fatigue. Methylphenidate, a controlled drug, and cognitive behavioural therapy have been used to manage fatigue, but ...
Chandrasekar Rathinam, Gemma Heath, Rajat Gupta, Evangeline Wassmer, Emily McElroy, Helen Horn, Davinia Fernandez‐Espejo   +6 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Patient advocacy and DSM-5

, 2015
The revision of the Diagnostic and Statistical Manual of Mental Disorders (DSM) provides a useful opportunity to revisit debates about the nature of psychiatric classification.
Stein, Dan J, Phillips, Katharine A
core   +1 more source

Negotiating research in the Emergency Department: a qualitative study of staff experience of the Distal Radius Acute Fracture Trial CAst versus SPlint (DRAFT3-CASP) RCT for distal radius fractures

Bone & Joint Open
Aims: We sought to explore staff experience of conducting an orthopaedic trauma randomized controlled trial (RCT) in the Emergency Department (ED). The Distal Radius Acute Fracture Trial: CAst versus SPlint (DRAFT3-CASP) RCT explores the effectiveness of
Emma E. Phelps, Elizabeth Tutton, Jenny Gould, Liz Baird, Juul Achten, Matthew L. Costa   +5 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Returning to work after breast cancer diagnosis: a cross-sectional study of socioeconomic and clinical factors associated with return to work in Luxembourg

BMC Women's Health
Background Breast cancer (BC) is one of the most common cancers affecting women globally, with consequences for health, quality of life, and socioeconomic status. Return-to-work (RTW) represents an important milestone for women affected by BC. This study
Allini Mafra, Mounir Talbi, Geraldine Cassells, Sandrine Lavalle, Marc Suhrcke, Martine Georges, Nicole Majery, Claudine Backes   +7 more
doaj   +1 more source

Patient involvement...or not? Analysis of 'Patient Involvement' statements in clinical trial publications in The BMJ

, 2018
Objective In 2014, The BMJ introduced a mandatory ‘Patient Involvement’statement in the Methods section of research articles. We investigated the extent of patient involvement described in clinical trial research publications in The BMJ. Our primary objective was to quantify patient authorship. Research design and methods We searched PubMed (journal:
Wadsworth, Anne-Clare, Arnstein, Lauri, Gegeny, Thomas, Jones, Rachel, Sargent, Arabella, Ciaglia, Antonio, Yamamoto, Beverley, Stephens, Richard, Woolley, Karen L.   +8 more
openaire   +2 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source