Results 61 to 70 of about 349,440 (263)

Conceptualising, operationalising and measuring trust in participatory health research networks: a scoping review protocol

BMJ Open, 2020
Introduction A participatory approach to co-creating new knowledge in health research has gained significant momentum in recent decades. This is founded on the described benefits of community-based participatory research (CBPR), such as increased ...
Meghan Gilfoyle, Anne MacFarlane, Jon Salsberg   +2 more
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Giving permission to care for people with dementia in residential homes: learning from a realist synthesis of hearing-related communication

BMC Medicine, 2019
Background Managing hearing communication for residents living with hearing loss and dementia in long-term care settings is challenging. This paper explores how care can be effective in optimising hearing communication for residents living with dementia.
Brian Crosbie, Melanie Ferguson, Geoff Wong, Dawn-Marie Walker, Stevie Vanhegan, Tom Dening   +5 more
doaj   +1 more source

Patient and Public Involvement for Dementia Research in Low- and Middle-Income Countries: Developing Capacity and Capability in South Asia [PDF]

, 2021
Jahanara Miah, Saima Sheikh, Rachel C. Francis, Gayathri Nagarajan, Sojan Antony, Maryam Tahir, Rabia Sattar, Anum Naz, Sehrish Tofique, Mostazir Billah, Sajib Saha, Iracema Leroi   +11 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Patient and public involvement within epidemiological studies of long COVID in the UK [PDF]

, 2023
Ash Routen, Lauren L. O’Mahoney, Olalekan Lee Aiyegbusi, Yvonne Alder, Amitava Banerjee, Lewis Buckland, Christopher E. Brightling, Melanie Calvert, Jennifer Camaradou, Nish Chaturvedi, Amy Chong, Emma Dalrymple, Rosalind M. Eggo, Paul Elliott, Rachael A Evans, Andy Gibson, Shamil Haroon, Emily Herrett, Linzy Houchen‐Wolloff, Sarah Hughes, Flic Jeyes, Karen Matthews, Christel McMullan, Jessica Morley, Roz Shafran, Nikki Smith, David Stanton, Terence Stephenson, Jonathan A C Sterne, Grace Turner, Helen Ward, Kamlesh Khunti   +31 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Implementing and Delivering Culturally Centred Pharmacy Services Tailored to Ethnically Minoritised Populations: A Qualitative Systematic Review and Meta‐Ethnography

Health Expectations
Introduction Health inequities disproportionately affect people from ethnic minority communities and require a comprehensive effort across healthcare disciplines to tackle them.
Caitlin Shaw, Ghalib Khan, Thorrun Govind, Anna Robinson‐Barella   +3 more
doaj   +1 more source

Google search data as a novel adjunct to patient and public involvement in rheumatology research [PDF]

, 2020
Mrinalini Dey, Sizheng Steven Zhao
openalex   +1 more source