Results 71 to 80 of about 1,068,059 (316)

Ethics and palliative care: a case of patient’s autonomy

open access: yesJournal of Medical Ethics and History of Medicine, 2023
The Article Abstract is not available.
openaire   +3 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Patient safety in health care professional educational curricula: examining the learning experience

open access: yes, 2009
This study has investigated the formal and informal ways pre-registration students from four healthcare professions learn about patient safety in order to become safe practitioners.
Steven, Alison   +2 more
core  

Biomedical ethics and genetic epidemiology [PDF]

open access: yes, 2004
Biomedical ethics developed in the late twentieth century as a challenge to the self- regulatory ethic that previously governed medical practice. Yet in recent years bioethics has come under scrutiny from the social sciences, which claim that the field ...
Whong-Barr, Michael
core  

Bodywork in dementia care: recognising the commonalities of selfhood to facilitate respectful care in institutional settings

open access: yes, 2014
This paper draws on two data sources (Kelly's ethnographic study and a British Broadcasting Corporation television programme) to explore the practice of bodywork in the care of frail people with dementia in institutional settings.
Kelly, Fiona, FIONA KELLY
core   +1 more source

Ethical Challenges in Clinical Care of Suicidal Patients

open access: yesIndian Journal of Social Psychiatry, 2023
Suicide management is attended with ethical dilemmas. Philosophical positions like respect for life (which generally accords with the theological position), autonomy, duty to others, and utilitarianism; as well as legal requirements provide a context for ethical decision making.
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Developing Patient-Centered Care Evaluation in a Long-Term Geriatric Care Setting

open access: yes, 2012
This paper proposes an evaluation model that assesses quality of care from a patient-centered care (PCC) perspective by incorporating the PCC concepts of empowerment, dignity, and respect, to determine whether the standard of care meets patient ...
Gras, Nathan
core  

Business Ethics and Health Care: The Re-Emerging Institution- Patient Relationship

open access: yes, 1999
Managed care poses a challenge to the traditional conceptualization of medicine and of the physician-patient relationship. People have evaluated the merits of managed care by focusing upon the way its incentives alter the relationship between physician ...
Peppin, John F.
core   +1 more source

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