Results 71 to 80 of about 1,579,916 (310)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Baseline Assessment of Providers\u27 Perspectives on Integrating Community Health Workers into Primary Care Teams to Improve Diabetes Prevention [PDF]

, 2017
• Type 2 Diabetes Mellitus (T2DM) affects 11% of U.S. adults • Additional 35% considered pre-diabetic, at-risk for developing T2DM1 • Bellevue Hospital and the VA NY Harbor Hospital disproportionately affected: 2x the prevalence in the general population,
Brown, Ariel, Gore, Radhika, Schwartz, MD, Mark, Wong, Garseng   +3 more
core   +1 more source

Supporting Collaborative Health Tracking in the Hospital: Patients' Perspectives [PDF]

, 2018
The hospital setting creates a high-stakes environment where patients' lives depend on accurate tracking of health data. Despite recent work emphasizing the importance of patients' engagement in their own health care, less is known about how patients ...
Elera, Rashmi G., Eschler, Jordan, Haldar, Shefali, Khelifi, Maher, Miller, Andrew D., Mishra, Sonali R., Pollack, Ari H., Pratt, Wanda   +7 more
core   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Advancing Patient Safety in the U.S. Department of Veterans Affairs [PDF]

, 2011
As part of a systemwide transformation, the VA formed its National Center for Patient Safety to foster an organizational culture of safety within its nationwide network of hospitals and outpatient clinics.
Deborah Chase, Douglas McCarthy
core  

Emerging strategies to target metastasis and therapy resistance in melanoma

Molecular Oncology, EarlyView.
Emerging studies propose new approaches to interfere with melanoma progression. In recognition of melanoma awareness month, at Molecular Oncology, we highlight recently published research articles, focusing on novel therapeutic targets driving metastatic spread and outlining different strategies to overcome resistance to BRAF inhibitors and anti‐PD‐1 ...
Amel Aziba
wiley   +1 more source

Trabalho em equipe e prática colaborativa na Atenção Primária à Saúde

Interface: Comunicação, Saúde, Educação
RESUMO Prática colaborativa e trabalho em equipe podem contribuir para melhorar o acesso universal e a qualidade da atenção à saúde. Entretanto, a operacionalização do trabalho interprofissional se constitui como um desafio atual.
Marina Peduzzi, Heloise Fernandes Agreli
doaj   +1 more source

Care for the critical patient undergoing point-of-care testing: integrative review [PDF]

Revista Brasileira de Enfermagem
Objective: to identify, based on the evidence, point-of-care testing in bedbound in critically ill patients. Method: integrative review, carried out through search in Pubmed, Virtual Health Library, Joanna Briggs Institute, The British Institute of ...
Débora Thais Siqueira Soares, Ana Paula Hermann, Maria Ribeiro Lacerda, Marineli Joaquim Méier, Nayla Tamara de Godoi Caceres, Juliana Zimmermann Lima   +5 more
doaj   +3 more sources

Personalizing Longitudinal Care Coordination for Patients with Chronic Kidney Disease [PDF]

, 2017
Chronic care coordination efforts often focus on the needs of the healthcare team and not on the individual needs of each patient. However, developing a personalized care plan for patients with Chronic Kidney Disease (CKD) requires individual patient ...
Cullen, Theresa A., Kasthurirathne, Suranga N., Narva, Andrew S., Norton, Jenna M.   +3 more
core  

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source